Interferon-γ down-regulates NKG2D ligand
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Nicole Schwinn; Daria Vokhminova; Antje Sucker; Sonja Textor; Sandra Striegel; I
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Article
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2009
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John Wiley and Sons
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French
⚖ 985 KB
## Abstract NKG2D operates as an activating receptor on natural killer (NK) cells and costimulates the effector function of αβ CD8^+^ T cells. Ligands of NKG2D, the MHC class I chain‐related (MIC) and UL16 binding protein (ULBP) molecules, are expressed on a variety of human tumors, including melan