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Gut microbiota regulates NKG2D ligand expression on intestinal epithelial cells

✍ Scribed by Hansen, Camilla H. F.; Holm, Thomas L.; Krych, Łukasz; Andresen, Lars; Nielsen, Dennis S.; Rune, Ida; Hansen, Axel K.; Skov, Søren


Book ID
118243787
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
887 KB
Volume
43
Category
Article
ISSN
0014-2980

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## Abstract NKG2D operates as an activating receptor on natural killer (NK) cells and costimulates the effector function of αβ CD8^+^ T cells. Ligands of NKG2D, the MHC class I chain‐related (MIC) and UL16 binding protein (ULBP) molecules, are expressed on a variety of human tumors, including melan