Guinea pig prostate contains one major soluble esteropeptidase activity. The protein has been purified and characterized and found to be a glycoprotein comprised of a single polypeptide chain. The molecular weight of the deglycosylated protein is approximately 26,000. The esteropeptidase has a simil
Guinea pig prostate is a rich source of nerve growth factor
β Scribed by HARPER, G. P.; BARDE, Y. A.; BURNSTOCK, G.; CARSTAIRS, J. R.; DENNISON, M. E.; SUDA, K.; VERNON, C. A.
- Book ID
- 109713945
- Publisher
- Nature Publishing Group
- Year
- 1979
- Tongue
- English
- Weight
- 371 KB
- Volume
- 279
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/279160a0
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Prostate glands of adult guinea pigs were stained for nerve growth factor (NGF) and epidermal growth factor (EGF) by immunohistochemical methods. Both NGF and EGF were localized diffusely in the cytoplasm of the glandular epithelial cells, and also in their secretory products. These findings suggest
## Abstract Nerve growth factor (NGF) has been purified from the guinea pig prostate using a modification of the BocchiniβAngeletti method for isolating 2.5S NGF from mouse submaxillary glands. As with the mouse preparation, guinea pig prostate NGF appears to migrate as a high molecular weight enti