The Isolation and Characterisation of Nerve Growth Factor from the Prostate Gland of the Guinea-Pig
β Scribed by Carey A. CHAPMAN; Charles A. VERNON; Barbara E. C. BANKS; John M. WALKER
- Book ID
- 115119929
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 510 KB
- Volume
- 115
- Category
- Article
- ISSN
- 1432-1327
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Nerve growth factor (NGF) has been purified from the guinea pig prostate using a modification of the BocchiniβAngeletti method for isolating 2.5S NGF from mouse submaxillary glands. As with the mouse preparation, guinea pig prostate NGF appears to migrate as a high molecular weight enti
Prostate glands of adult guinea pigs were stained for nerve growth factor (NGF) and epidermal growth factor (EGF) by immunohistochemical methods. Both NGF and EGF were localized diffusely in the cytoplasm of the glandular epithelial cells, and also in their secretory products. These findings suggest
Guinea pig prostate contains one major soluble esteropeptidase activity. The protein has been purified and characterized and found to be a glycoprotein comprised of a single polypeptide chain. The molecular weight of the deglycosylated protein is approximately 26,000. The esteropeptidase has a simil