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Guanine-nucleotide exchange factors: a family of positive regulators of Ras and related GTPases

✍ Scribed by Feig, Larry A.

Book ID
123296078
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
1009 KB
Volume
6
Category
Article
ISSN
0955-0674

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## Abstract Members of the Ras superfamily of proteins function as regulated GDP/GTP switches that cycle between active GTP‐complexed and inactive GDP‐complexed states. Guanine nucleotide exchange factors (GEFs) stimulate formation of the GTP‐bound state, whereas GTPase activating proteins (GAPs) c