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A novel membrane factor stimulates guanine nucleotide exchange reaction of ras proteins

✍ Scribed by Michael West; Hsiang-fu Kung; Tohru Kamata

Book ID
115922889
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
555 KB
Volume
259
Category
Article
ISSN
0014-5793

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## Abstract Members of the Ras superfamily of proteins function as regulated GDP/GTP switches that cycle between active GTP‐complexed and inactive GDP‐complexed states. Guanine nucleotide exchange factors (GEFs) stimulate formation of the GTP‐bound state, whereas GTPase activating proteins (GAPs) c