Guaianolides : The total synthesis of (±
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M. Demuynck; A.A. Devreese; P.J. De Clercq; M. Vandewalle
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Article
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1982
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Elsevier Science
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French
⚖ 249 KB
An efficient synthesis of the trans fused perhydroazulenic epoxy ketone 2 is described. The potentiality of 2 is illustrated by its transformation into cf)-estafiatin 1. Despite a long history, a wide distribution in nature, and extensive studies in relation to interconversions with other sesquiter