𝔖 Bobbio Scriptorium
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An intermediate for the total synthesis of guaianolides

✍ Scribed by Peter Metz; Hanz-J. Schäfer


Book ID
104221668
Publisher
Elsevier Science
Year
1982
Tongue
French
Weight
210 KB
Volume
23
Category
Article
ISSN
0040-4039

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Guaianolides : The total synthesis of (±
✍ M. Demuynck; A.A. Devreese; P.J. De Clercq; M. Vandewalle 📂 Article 📅 1982 🏛 Elsevier Science 🌐 French ⚖ 249 KB

An efficient synthesis of the trans fused perhydroazulenic epoxy ketone 2 is described. The potentiality of 2 is illustrated by its transformation into cf)-estafiatin 1. Despite a long history, a wide distribution in nature, and extensive studies in relation to interconversions with other sesquiter