GSTM1, GSTT1, and GSTP1 polymorphism and lung cancer risk in relation to tobacco smoking
β Scribed by Joachim Schneider; Ulrike Bernges; Monika Philipp; Hans-Joachim Woitowitz
- Book ID
- 116333034
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 130 KB
- Volume
- 208
- Category
- Article
- ISSN
- 0304-3835
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π SIMILAR VOLUMES
Several polymorphic glutathione S-transferase enzymes are involved in the detoxification of active metabolites of many potential carcinogens from tobacco smoke and may therefore be important in modulating susceptibility to smoking-related cancers. As part of a hospital-based case-control study perfo
## Abstract Earlyβonset lung cancer diagnosed up to the age of 50 is a very rare disease, with an increasing incidence rate. Differences in aetiology, characteristics and epidemiology of early and older onset lung cancer have been described previously, suggesting the importance of genetic factors i