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Growth stimulation of a human colorectal carcinoma cell line by interleukin-1 and -6 and antagonistic effects of transforming growth factor β1

✍ Scribed by Lahm, Harald; Petral-Malec, Danuta; Yilmaz-Ceyhan, Aysim; Fischer, Jürgen R; Lorenzoni, Murielle; Givel, Jean-Claude; Odartchenko, Nicolas

Book ID
122041609
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
801 KB
Volume
28
Category
Article
ISSN
0959-8049

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Transforming growth factor β1 (TGF-β1) inhibits growth of a human ovarian carcinoma cell line (OVCCR1) and is expressed in human ovarian tumors
✍ S. Jozan; M. Guerrin; P. Mazars; M. Dutaur; B. Monsarrat; F. Cheutin; R. Bugat; 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 French ⚖ 957 KB

## Abstract The effects of EGF and TGF‐β1 on the proliferation of 2 ovarian carcinoma cell lines (IGROV1 and OVCCR1) were evaluated. The cell lines were adapted to grow in a restricted serum (0.5%) medium. EGF was required for proliferation of both ovarian cell lines. Low doses of TGF‐β1 inhibited