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Growth of AKR T Cell Leukemia Lyphoblasts in Medium Containing Interleukin 2 (IL-2)

✍ Scribed by Chiu-Yang Shih, Robert L. Truitt, Marco Andreani and Mortimer M. Bortin


Book ID
124864505
Publisher
Society for In Vitro Biology
Year
1983
Tongue
English
Weight
279 KB
Volume
19
Category
Article
ISSN
1475-2689

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A selected clone from an IL-2-dependent human T-cell line was persistently propagated in the presence of phorbol esters with the ability to activate protein kinase C (PKC), such as 12-0-tetradecanoylphorbol-I 3-acetate (TPA) or phorbol-12,1.3-dibutylate (PDBu). Thus, a TPA(PD6u)-dependent T-cell lin