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Growth Hormone Treatment for Growth Failure in Pediatric Patients with Crohn's Disease

โœ Scribed by Melvin B. Heyman; Elizabeth A. Garnett; Janet Wojcicki; Neera Gupta; Cheryl Davis; Stanley A. Cohen; Benjamin D. Gold; Barbara S. Kirschner; Robert N. Baldassano; George D. Ferry; Harland S. Winter; Selna Kaplan


Book ID
113744707
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
280 KB
Volume
153
Category
Article
ISSN
1097-6833

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Background: Growth failure remains a common complication of pediatric Crohn's disease (CD) and has been associated with small bowel involvement and need for surgery. We have reported that patients with elevated (!1.6 lg/mL) granulocyte macrophage colony stimulating factor autoantibodies (GM-CSF Ab)

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Growth retardation (GR) may pose a significant challenge to the quality of life and the proper management of children and adolescents with Crohn's disease (CD). It can occur in a significant proportion of patients, and may precede clinical evidence of bowel disease. Current evidence suggests that GR