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Growth hormone, insulin-like growth factor 1, and insulin signaling—a pharmacological target in body wasting and cachexia

✍ Scribed by Katja Trobec; Stephan von Haehling; Stefan D. Anker; Mitja Lainscak


Book ID
107703877
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
290 KB
Volume
2
Category
Article
ISSN
2190-5991

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Cirrhosis is characterized by paradoxical growth hormone secretion in response to glucose and insulin infusion. To ascertain whether this abnormality contributes to insulin resistance, euglycemic hyperinsulinemic glucose clamps were performed on six patients with cirrhosis and six normal control sub