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Growth and metabolism of hybridomas immobilized in packed beds: comparison with static and suspension cultures

✍ Scribed by A.D. Murdin; J.S. Thorpe; D.J. Groves; R.E. Spier


Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
447 KB
Volume
11
Category
Article
ISSN
0141-0229

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## Abstract The steady‐state metabolic parameters for a hybridoma cell line have been determined in continuous suspension–perfusion culture over a wide range of perfusion rates and cell bleed rates. Significant increases in viable cell concentrations and volumetric productivities were achieved at h