Growth and differentiation of Friend erythroleukemia cells in serum-free culture
โ Scribed by Cristina Jemma; Giovanni Battista Rossi
- Book ID
- 113238239
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 411 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0145-2126
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๐ SIMILAR VOLUMES
Dimethylsulfoxide (DMSO) converts almost all of the undifferentiated murine erythroleukemia cells (MEL or Friend cells, clone 745A) in a culture to differentiated cells that contain high levels of hemoglobin and that stop growing after a limited number of cell divisions. Contrary to other reports-th
Friend erythroleukemia cells (FELC) served as a model system for cell differentiation because these cells can be triggered to differentiate by a variety of chemical agents. Treatment with the classical inducer of differentiation, hexamethylene bisacetamide (HMBA), stimulated superoxide dismutase (SO
Binding experiments with the specific muscarinic ligand [ 3 H]N-methylscopolamine ( 3 H-NMS) have shown the presence of constitutive muscarinic acetylcholine receptors (mAChR) on Friend murine erythroleukemia cells (MELC). Competition experiments with a panel of specific antagonists indicated that t