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Group testing in presence of classification errors

โœ Scribed by Diwakar Gupta; Regina Malina

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
143 KB
Volume
18
Category
Article
ISSN
0277-6715

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โœฆ Synopsis

We modify Dorfman's and Sterrett's group testing protocols to make them suitable for testing blood samples for the presence of HIV antibodies, as well as for many industrial applications, when false negatives cannot be tolerated. We รฟrst propose that test kit sensitivity be increased to nearly 100 per cent by altering the reactive versus non-reactive threshold. Subsequently, group and repeat testing are used with a careful selection of group size and the number of times a test is repeated, in order to maximize e ciency while keeping the false positive predictive value (FPPV) within a speciรฟed limit. Numerical calculations show that our testing protocol is e cient, has low procedural complexity and keeps both types of classiรฟcation errors below speciรฟed tolerance limits.

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