The distribution of Gc subtypes in a sample of the Chinese population of Hong Kong was studied using isoelectric focusing followed by immunofixation. A sensitive modification of this technique is described. Nine distinct phenotypes were observed which appear to result from the three common alleles G
Group-specific component (Gc) subtypes in two chinese populations
β Scribed by Zhi-min Zeng; Keiichi Omoto
- Publisher
- Nature Publishing Group
- Year
- 1987
- Tongue
- English
- Weight
- 430 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1435-232X
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Simultaneous subtyping of two genetic markers--group-specific component (Gc) and transferrin (Tf)--by electrofocusing enabled us to compute the following gene frequencies for the Tunisian population: Gc1S, 0.525; Gc1F, 0.260; Gc2, 0.215; TfC1, 0.770; TfC2, 0.215; TfD1, 0.015. The frequencies of TfD,
Simultaneous subtyping of Gc and TfC by isoelectric focusing allows us to compute the following gene frequencies for the Belgian population: Gc1S = 0.543 Gc1F = 0.167 Gc2 = 0.290 TfC1 = 0.784 TfC2 = 0.206 TfB = 0.007 TfD = 0.003. The Gc bands were precipitated by sulfosalicylic acid instead of by im