Disruption/deletion mutations in genes of the RAD52 epistasis group of Saccharomyces cerevisiae were examined for their effects on recombination between single- and double-stranded circular DNA substrates and chromosomal genes in a transformation assay. In rad50 mutants there was a small reduction i
Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants
β Scribed by Kolodner, Richard D.; Chen, Clark
- Book ID
- 109494810
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 122 KB
- Volume
- 23
- Category
- Article
- ISSN
- 1061-4036
- DOI
- 10.1038/12687
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Two rad mutants of yeast, rad10 and rad16, are shown to be defective in the removal of UV-induced pyrimidine dimers since DNAs obtained from irradiated cells following a post-irradiation incubation in the dark still retain UV-endonuclease-sensitive sites. Both rad10 and rad16 mutants are in the same
The metal ions, Cu 2+/+ and Fe 3+/2+ , are essential co-factors for a wide variety of enzymatic reactions. However, both metal ions are toxic when hyper-accumulated or maldistributed within cells due to their ability to generate damaging free radicals or through the displacement of other physiologic