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Grob Fragmentation of 2-Azabicyclo[2.2.2]oct-7-ene: Tool for the Stereoselective Synthesis of Polysubstituted Piperidines

✍ Scribed by Lemonnier, Gérald; Charette, André B.


Book ID
111887941
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
443 KB
Volume
77
Category
Article
ISSN
0022-3263

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New synthesis of 7-(tert-butoxycarbonyl)
✍ Lawrence E. Brieaddy; Feng Liang; Philip Abraham; Jeffrey R. Lee; F. Ivy Carroll 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 110 KB

A new, high yield, convenient synthesis of 7-(tert-butoxycarbonyl)-7-azabicyclo[2.2.1 ]hept-2erie which involved the addition of tributyltin hydride to 7-(tert-butoxycarbonyl)-2-p-toluenesulfonyl-7azabicyclo[2.2.1]-2-ene followed by elimination of the tributyltin and p-tolylsulfonyl groups using tet