Allylic oxidation of 4-allyl-1-dimethyl-t-butylsilylazetidin-2ones (5,7) gave the 4-(l-hydroxyprop-2-ene-1-yl) derivatives (6,8). Radical benzoyloxylation of the silylated 8-oxo-7-azabicyclo[4.2.O]oct-3ene (18) provided four allylic monobenzoates. Progression of ( ) and ( ) afforded, respectively,
Synthesis of the 3-acetoxy-7-oxo-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylate system
β Scribed by John H Bateson; Stephen C.M Fell; Robert Southgate
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- French
- Weight
- 192 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The synthesis of the title compound (4) is described. ## Treatment of (3S)-[(lR)-hydroxyethyl]-(4R)- [ 3-(p-nitrobenzyloxy) carbonyl-2-0x0-[ 2-I4C] -3-diazopropan-l-yl]azetidin-2-one1 with rhodium diacetate achieved ring closure forming (5R,6S)-pnitrobenzyl-6-~(1R)-hydroxyethyl]-3,7-dioxo-[3-14C]
The synthesis of a d'carbapenem and two ,?-lactams possessing a Br-atom at the N-substituting center not involved in the lactam ring and bearing the carboxyl group is described. The ,?-lactams having this kind of Br-substitution are more susceptible to nucleophilic attack than those having a conjuga
The title compound was prepared in good yield via intramolecular insertion of an a-alkoxycarbonyl, a-sulphonyl carbene into the N-H bond of an azetidinone. Esters of (k) 7-oxo-3-thia-l-azabicyclo[3.2.0lheptane-2-carboxylate-3,3-dioxide, 1, are potentially useful intermediates in the synthesis of no