Background: Fibrostenotic lesions are common complications in Crohn's disease (CD) often requiring surgery. Inherited thrombotic risk factors are associated with fibrosis in other chronic inflammatory diseases. The aim of the study was to assess whether inherited thrombotic risk factors are associat
GRIM-19 mutations are not associated with Crohn's disease
✍ Scribed by António Carlos Ferreira; Lígia Gomes; Valdemar Máximo; Jorge Amil; Fátima Carneiro; José Carlos Machado; Fernando Tavarela-Veloso
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 224 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1078-0998
No coin nor oath required. For personal study only.
✦ Synopsis
FIGURE 1. Alignment of the GRIM-19 protein sequence (Homo sapiens, Pan troglodytes, Canis familiaris, Bos taurus, Mus musculus, and Fugu rubripes).
📜 SIMILAR VOLUMES
FIG. 1. MRI showed symmetric (A) hypointensity signal on T1weighted imaging and (B) hyperintensity signal on T2-weighted imaging in bilateral substantia nigra on admission. A repeated MRI after 3 months showed resolution of the lesions on (C) T2-weighted imaging and (D) T1-weighted imaging.
## Abstract Recent studies have reported an association between the glucocerebrosidase (__GBA__) gene and Parkinson's disease (PD). To elucidate the role of this gene in our population, we screened 395 PD patients and 483 controls from southern Italy for the N370S and the L444P mutations. We found