Well-designed and conducted Phase 11 clinical trials are very important to cancer chemoprevention drug development. Three critical aspects govern the design and conduct of these trials-wellcharacterized agents, suitable cohorts, and reliable biomarkers for measuring efficacy that can serve as surrog
โฆ LIBER โฆ
Green Tea Polyphenols and Cancer Chemoprevention: Multiple Mechanisms and Endpoints for Phase II Trials
โ Scribed by Susan B. Moyers; Nagi B. Kumar
- Book ID
- 111435536
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 224 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0029-6643
No coin nor oath required. For personal study only.
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The Cancer and Leukemia Group B (CALGB) conducted sequential Phase II multicenter trials to evaluate the activity of edatrexate alone (E) or with leucovorin rescue (EL) in patients with malignant pleural mesothelioma (CALGB Protocol 9131).