## Abstract **BACKGROUND**: Hyperthermia (HS) is a wellβstudied teratogen that induces serious malformations, including neural tube defects. Our previous studies have shown that HS induces apoptosis by activating the mitochondrial apoptotic pathway. Prior to activation of the mitochondrial apoptoti
Great arteries: Normal development and malformations induced in the rat and mouse
β Scribed by Alice M. Druga; Mariann Nyitray
- Book ID
- 113875315
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 63 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0890-6238
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Transposition of the great arteries (TGA) is the most common cyanotic cardiac malformation, representing 5-7% of all cardiac malformations. Previous estimates of the frequency of cardiac malformations in sibs of probands range from 0-1.7%. This study ascertained the frequency of congenital cardiac m
At various gestational periods, caffeine was injected intra-arterially or intraperitoneally into pregnant rats. The teratogenic effects of caffeine on the fetal heart were dose dependent and detectable at relatively low concentrations. The most susceptible stage was during septation of the heart. Th