Graphical and stereolithographic models of the developing human heart lumen

✍ Scribed by J.O. Pentecost; D.J. Sahn; B.L. Thornburg; M. Gharib; A. Baptista; K.L. Thornburg

• Publisher: Elsevier Science
• Year: 2001
• Tongue: English
• Weight: 119 KB
• Volume: 25
• Category: Article
• ISSN: 0895-6111
• DOI: 10.1016/s0895-6111(01)00020-9

✦ Synopsis

Scaled physical models can be useful in analyzing stage-speci®c hemodynamics in the embryonic human heart to address correlations between early physical stressors and myocardial wall responses. We generated models of the cardiac blood space from reconstructions of four digitized human embryo images from Carnegie Collection at the Armed Forces Institute of Pathology. From physical scale models manufactured by stereolithography, compliant sleeves can be created for ¯ow dynamics studies. This novel use of Carnegie collection images and graphical modeling software provides tools for broadening our understanding of normal and aberrant heart formation.