## Abstract Defects originating from the atrioventricular canal region are part of a wide spectrum of congenital cardiovascular malformations that frequently affect newborns. These defects include partial or complete atrioventricular septal defects, atrioventricular valve defects, and arrhythmias,
Accessory atrioventricular muscle bundles of the developing human heart
β Scribed by Truex, R. C. ;Bishof, J. K. ;Hoffman, E. L.
- Publisher
- John Wiley and Sons
- Year
- 1958
- Tongue
- English
- Weight
- 793 KB
- Volume
- 131
- Category
- Article
- ISSN
- 0003-276X
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β¦ Synopsis
It is an accepted anatomic fact that the atrial and ventricular myocardium of the human heart are continuous solely by means of the common bundle (crus communis, bundle of His) of conduction tissue. The original observations of His ( ) have been substantiated by numerous investigators, and in the vast majority of human hearts examined, the common bundle is the only muscular bridge between the atria and ventricles. Modern physiologic concepts of the meclianism of normal intracardiac conduction, as well as the interpretation of electrocardiographic records, are based on this morphologic atrioventricular bundle.
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## Background: We investigated potential early asymmetries in the distribution of mesenchymal cells within the inferior and superior av cushions in the developing chick heart. ## Methods: Chick embryos stages 16-20 hh were fixed, embedded in polyacrylamide, and the cell nuclei stained with propid