Granuloma pouch assay for mutagenicity t
β
P. Maier
π
Article
π
1980
π
Springer-Verlag
π
English
β 321 KB
The Granuloma Pouch Assay (GPA) is an animal model in which mutagenic and carcinogenic effects of a testcompound can be detected in rapidly dividing fibroblasts of a granulation tissue in adult male rats. Growth of this tissue was initiated with a small amount of croton oil at the inside wall of a s