## Abstract Animal cancer models reduce genetic background heterogeneity and thus, may facilitate identification and analysis of specific genetic aberrations in tumor cells. Rat and human mammary glands have high similarity in physiology and show comparable hormone responsiveness. Thus, spontaneous
Absence of cinoxacin-induced DNA fragmentation and mutations in the rat granuloma pouch
β Scribed by Albiana Pino; Annalisa Maura; Patrizia Grillo
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 338 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0893-6692
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Granulomas were produced over the calvaria of rats by injection of a mixture of turpentine and peanut oil. The granulomas induced localised areas of bone resorption and these resorptive lesions were examined at the fine structural level. A close association was found between osteoclasts and fibrobla