## BACKGROUND. Bronchial epithelial cells produce a significant amount of granulocyte-macrophage-colony stimulating factor (GM-CSF), which is believed to mediate both the host defense and inflammation. Recently, GM-CSF has been demonstrated to be produced by several tumor cells and also to be asso
Granulocyte-colony stimulating factor promotes invasion by human lung cancer cell linesin vitro
β Scribed by Xin-Hai Pei; Yoichi Nakanishi; Koichi Takayama; Jun Yatsunami; Feng Bai; Masayuki Kawasaki; Kentaro Wakamatsu; Nobuko Tsuruta; Keiko Mizuno; Nobuyuki Hara
- Publisher
- Springer
- Year
- 1996
- Tongue
- English
- Weight
- 547 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0262-0898
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## Background and objectives: We describe a case of granulocyte colony-stimulating factor (gcsf) and interleukin-6 (il-6)-producing lung cancer. ## Methods: A 53-year-old man underwent left upper lobectomy under diagnosis of lung cancer. the tumor obtained by a preoperative biopsy was analyzed.
Granulocyte/macrophage colony-stimulating factor (GM-CSF) is an important hematopoietic growth factor which has been shown to induce proliferation and activation of inflammatory cells, and may play a role in allergic diseases and experimental allergic reactions. Since little is known about the invol
## Abstract We previously established 2 lung cancer cell lines, OKaβCβ1 and MIβ4, which constitutively produce an abundant dose of granulocyteβcolony stimulating factor (GβCSF) and granulocyte macrophageβcolony stimulating factor (GMβCSF). Many other cases with GβCSF or GMβCSF producing tumors have