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Granulocyte colony-stimulating factor (G-CSF) administration in individuals with sickle cell disease: time for a moratorium?

โœ Scribed by Fitzhugh, Courtney D.; Hsieh, Matthew M.; Bolan, Charles D.; Saenz, Carla; Tisdale, John F.


Book ID
122200245
Publisher
Informa plc
Year
2009
Tongue
English
Weight
179 KB
Volume
11
Category
Article
ISSN
1465-3249

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A therapeutic trial of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) was attempted in a patient with neutropenia and frequent infections secondary to T-y lymphoproliferative disease (T-y LPD). During the 14 days of subcutaneous rhGM-CSF (500 kg/m2/day), the absolute e