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Grainger & Allison's Diagnostic Radiology: 2-Volume Set

✍ Scribed by Andy Adam, Adrian K. Dixon, Jonathan H Gillard, Ronald G. Grainger


Publisher
Churchill Livingstone
Year
2014
Tongue
English
Leaves
3589
Edition
6
Category
Library

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✦ Synopsis


Long recognized as the standard general reference in the field, this completely revised edition of  Grainger and Allisons Diagnostic Radiology provides all the information that a trainee needs to master to successfully take their professional certification examinations as well as providing the practicing radiologist with a refresher on topics that may have been forgotten. Organized along an organ and systems basis, this resource covers all diagnostic imaging modalities in an integrated, correlative fashion and focuses on those topics that really matter to a trainee radiologist in the initial years of training.

"...the latest edition ...  continues the fine tradition set by its predecessors.... help young radiologists to prepare for their examinations and continue to be a source of information to be dipped in and out of ... senior radiologists will also find the book useful ..."Reviewed by: RAD Magazine March 2015

 "I am sure the current edition will be successful and help young radiologists to prepare for their examinations and continue to be a source of information to be dipped in and out of..."Reviewed by RAD Magazine, March 2015

  • Master the field and prepare for certification or recertification with a succinct, comprehensive account of the entire spectrum of imaging modalities and their clinical applications.

    • Effectively apply the latest techniques and approaches with complete updates throughout including 4 new sections (Abdominal Imaging, The Spine, Oncological Imaging, and Interventional Radiology) and 28brand new chapters.

    • Gain the fresh perspective of two new editors-Jonathan Gillard and Cornelia Schaefer-Prokop -- eight new section editors -- Michael Maher, Andrew Grainger, Philip O'Connor, Rolf Jager, Vicky Goh, Catherine Owens, Anna Maria Belli, Michael Lee -- and 135 new contributors.

      • Stay current with the latest developments in imaging techniques such as CT, MR, ultrasound, and coverage of hot topics such as: Image guided biopsy and ablation techniques and Functional and molecular imaging.

      • Solve even your toughest diagnostic challenges with guidance from nearly 4,000 outstanding illustrations.

      • Quickly grasp the fundamentals you need to know through a more concise, streamlined format.

      • Access the full text online at Expert Consult.

    ✦ Table of Contents


    GRAINGER & ALLISON’S DIAGNOSTIC RADIOLOGY A Textbook of Medical Imaging: Volume I
    Grainger & Allison’s Diagnostic Radiology
    Copyright page
    Table of Contents
    Preface
    List of Section Editors
    List of Contributors
    A Principles of Imaging Techniques and General Issues
    1 Medical Physics:
    Chapter Outline
    Radiation Risks
    Deterministic and Stochastic Effects
    Fetal Exposure
    Legislation and Principles of Radiation Protection
    Patient Doses in Diagnostic Imaging
    Estimating Patient Doses
    Typical Patient Doses
    Detectors for Radiography and Fluoroscopy
    Optimising Patient Dose
    Optimising Patient Dose in Nuclear Medicine
    Areas of Special Attention
    Pregnancy and Potential Pregnancy
    Infants and Children
    Research Exposures
    Health Screening Programmes
    High-Dose Techniques
    Radiation Protection of Staff and Public
    Distance, Time and Shielding
    Personal Protection in Nuclear Medicine
    Radiation Hazards from Nuclear Medicine Patients
    Dose Monitoring
    Pregnant Staff
    Clinical Application of Radiation Dose Optimisation in CT
    Introduction
    Terms Describing CT Dose
    Standard Dose
    Low Dose
    Radiation Dose Descriptors in CT
    Volume Computed Tomography Dose Index (CTDIvol)
    How to Set Up a Dose Optimisation Process
    AEC System: Principles and Pitfalls
    Two Methods for Validating Dose Optimisation
    Parameter Optimisation
    Adequate References as Goals for Optimisation
    Up-to-Date Optimised CT Parameters
    CT of the Brain
    CT of the Thorax
    CT of the Lumbar Spine
    Summary and Conclusion
    Further Reading
    Online-only References
    2 Intravascular Contrast Media for Radiography, CT, MRI and Ultrasound
    Chapter Outline
    Introduction
    Contrast Media for Radiography and CT
    Barium-Based Contrast Agents
    Iodine-Based Contrast Media
    High-Osmolar Ionic Contrast Media (Fig. 2-3)
    Low-Osmolar Ionic Contrast Media (Fig. 2-4)
    Quantity of Contrast Medium Required
    Contrast Media for MR Imaging
    Gadolinium-Based Contrast Media
    Pharmacokinetics
    Quantity of Contrast Medium Required
    Iron-Based Contrast Media
    Manganese-Based Contrast Media
    Tissue-Specific MR Contrast Agents
    Use of Extracellular MR Contrast Agents for Radiographic Examinations
    Contrast Media for Ultrasound
    Microbubbles
    Pharmacokinetics
    Effect on Echogenicity
    Safety
    Recommendations
    Potential Developments
    Informed Consent
    Summary of Product Characteristics (sPc)
    Off-Label Use
    Adverse reactions
    Types of Reactions
    Idiosyncratic Reactions
    Chemotoxic Reactions
    Acute Non-renal Adverse Reactions
    Incidence
    Risk Factors
    Prevention
    Acute Renal Adverse Reactions (Contrast-Induced Nephropathy)
    Late Adverse Reactions
    Very Late Adverse Reactions
    Thyrotoxicosis
    Pregnancy and Lactation
    Interaction
    Extravasation
    Measurement of Glomerular Filtration Rate
    Further Reading
    Online-only References
    3 Ultrasound
    Chapter Outline
    Nature of Ultrasound
    Ultrasonic Transducers
    Propagation in Tissue
    Attenuation
    Reflection
    Ultrasound Methods
    The Pulse-Echo Method
    Beam Steering
    Resolution
    Artefacts
    Interpretative Principles
    Shadowing and Increased Through Transmission
    Echogenicity
    Doppler
    Theoretical Basis of Doppler Studies
    Characteristics of Blood Flow
    Information in the Doppler Signal
    Pulsatility Measurements
    Spectral Content
    Colour Doppler
    Power Doppler
    Volume Flow Measurement
    Doppler Artefacts, Errors and Pitfalls
    Sample Volume Size and Position
    Velocity Information
    Wall Filters
    Colour Artefacts
    Contrast Agents
    Safety
    Developments in Ultrasound
    High Frequencies, 3D, Elastography
    Ultrasound Therapy
    Acknowledgements
    Further Reading
    Physics
    Clinical
    Safety
    New Developments
    4 Computed Tomography
    Chapter Outline
    Computed Tomography (CT): A Brief History
    Principles of Computed Tomography
    CT Numbers and Image Matrix
    Generations of CT Development
    X-Ray Tubes
    X-Ray Detectors
    Slice Wars and Beyond
    Image Reconstruction
    Filtered Back Projection
    Iterative Reconstruction
    Helical CT
    Reconstruction of Arbitrary Section Thickness and Orientation
    Image Quality and Radiation Dose
    Contrast Media
    Preparation
    Contrast Medium Injection
    Potential Complications
    Gastrointestinal Contrast Agents
    Optimising Image Acquisition
    CT Protocols
    Planning
    Image Analysis
    CT-Guided Interventions
    Planning and Patient Preparation
    Procedure
    Follow-Up
    Advanced Techniques
    Cardiac CT
    Dual-Energy CT
    Subtraction Imaging
    CT Perfusion
    Motion Analysis
    Further Reading
    Online-only References
    5 Magnetic Resonance Imaging
    Chapter Outline
    Historical Perspective
    Spin Physics
    Excitation and Relaxation: Free Induction Decay and Echoes
    Signal Localisation: Techniques for Building Images
    2D Encoding
    3D Encoding
    Fast and Alternative k-space Tranversal
    Parallel Imaging
    Pulse Sequences
    Variations on a Spin Echo
    Basic Two-Dimensional Spin-Echo Sequence
    Multi-Spin Echo
    Single-Shot Fast Spin Echo (SS-FSE) or Half-Fourier Acquired Single-Shot Turbo Spin Echo (HASTE)
    Variations on a Gradient Echo/Field Echo
    Basic Two-Dimensional Gradient-Echo Sequence
    Three-Dimensional Gradient Echo
    Magnetisation Prepared Rapid Acquisition Gradient Echo (MP-RAGE) or Turbo-FLASH or Inversion Recovery-Prepared Fast Spoiled Gradient-Recalled Echo
    Instrumentation
    Magnets
    Gradients
    Radiofrequency
    Computers
    Physical Parameters That Provide Contrast
    Proton Density
    T1 (Longitudinal Relaxation Time or Spin–Lattice Relaxation Time)
    T2 (Transverse Relaxation Time or Spin–Spin Relaxation Time)
    T2* and Endogenous Susceptibility
    Exogenous Contrast Agents
    Chemical Shift
    Proton Spectroscopy
    Water/Fat Imaging
    Flow
    Time-of-Flight MRA
    Phase Contrast MRA
    Non-Contrast-Enhanced MRA (Fresh Blood Imaging)
    Non-Contrast-Enhanced MRA (Balanced Steady-State Free Precession)
    Perfusion (Microvascular Flow)
    Diffusion
    Safety Considerations
    Static Magnetic Field
    Time-Varying Magnetic Field Gradients
    Radiofrequency Field
    Conclusion
    Further Reading
    Online-only References
    6 Radionuclide and Hybrid Imaging
    Chapter Outline
    Introduction and General Principles
    Basic Physics
    Structure of the Atom
    Radioactivity
    Alpha Radiation
    Beta Radiation
    Positron Emission
    X and Gamma Radiation
    Definitions
    Interaction of X and Gamma Radiation with Matter
    The Gamma Camera
    Detection System
    Collimators
    Temporal Resolution
    Techniques of Image Acquisition and Processing
    Gamma Camera Limitations
    Principles of Emission Tomography (PET and SPECT)
    Tomographic Reconstruction
    SPECT Design and Characteristics
    PET Design and Characteristics
    Hybrid Systems: SPECT-CT, PET-CT and PET-MRI
    Quantification and Image Processing
    General Processing
    Quantification
    Image Registration
    Image Interpretation
    Non-Imaging Applications
    Radiopharmaceuticals
    Further Reading
    Online-only References
    7 Functional, Physiological and Molecular Imaging
    Chapter Outline
    Physiological Imaging with Contrast Media
    Why Use Kinetic Modelling?
    Contrast Agent Pharmacokinetics
    Measurement of Tracer Concentration
    Modelling and Mathematical Approaches
    Perfusion
    Fractional Vascular Volume
    Other Functional Indices
    Summary
    Principles of Molecular Imaging
    Molecular Imaging and Hypoxia Inducible Factor-1
    Direct Molecular Imaging
    Indirect Molecular Imaging
    Comparison of Molecular Imaging Strategies
    Molecular Imaging and Biotechnology
    Applications of Molecular Imaging
    Combined Physiological and Molecular Imaging
    Summary
    Appendices
    Appendix 1
    Appendix 2
    Appendix 3
    Appendix 4
    Appendix 5
    Further Reading
    Online-only References
    B The Chest and Cardiovascular System
    8 Techniques in Thoracic Imaging
    Chapter Outline
    Chest Radiography
    Equipment Considerations
    Additional Radiographic Views
    Portable Chest Radiography
    Novel Radiographic Techniques
    Computed Tomography of the Thorax
    Dual-Energy CT
    Dose Considerations
    Intravenous Contrast Medium Enhancement and Timing of CT Data Acquisition
    Window Settings
    High-Resolution Computed Tomography
    Ultrasound
    Endoscopic and Endobronchial Ultrasound
    Magnetic Resonance Imaging
    Ventilation–Perfusion Scintigraphy
    Further Reading
    Online-only References
    9 The Normal Chest
    Chapter Outline
    The Lungs
    The Central Airways
    The Lungs Beyond the Hila
    The Hila
    The Mediastinum
    Computed Tomography and Magnetic Resonance Imaging
    Radiographic Appearances
    Junction Lines
    Left Mediastinum above the Aortic Arch
    Right Middle Mediastinal Border below the Azygos Arch
    Retrosternal Line
    The Diaphragm
    Further Reading
    Online-only References
    10 The Chest Wall, Pleura, Diaphragm and Intervention
    Chapter Outline
    The Chest Wall
    Soft Tissues
    Breasts
    Subcutaneous Emphysema
    Bony Structures
    Ribs
    Clavicles
    Spine
    The Pleura
    Pleural Effusion
    Imaging Pleural Effusion
    Some Specific Pleural Effusions
    Pneumothorax
    Primary Spontaneous Pneumothorax
    Secondary Spontaneous Pneumothorax
    Complications
    Pleural Thickening and Fibrothorax
    Pleural Calcification
    Pleural Tumours
    Localised Pleural Tumours
    Diffuse Pleural Tumours
    The Diaphragm
    Level
    Eventration
    Movement and Paralysis
    Diaphragmatic Hernias
    Diaphragmatic Trauma
    Neoplasms of the Diaphragm
    Further Reading
    Online-only References
    11 The Mediastinum, Including the Pericardium
    Chapter Outline
    Mediastinal Diseases
    Mediastinal Masses
    Incidence
    Approach to Mediastinal Masses
    Parathyroid Masses
    Lymphofollicular Thymic Hyperplasia and Rebound Thymic Hyperplasia
    Mediastinal Lymphadenopathy
    Foregut Duplication Cysts
    Mediastinal Pancreatic Pseudocyst
    Mesenchymal Tumours and Tumour-Like Conditions
    Fat-Containing Hernias
    Other Mediastinal Lesions
    Acute Mediastinitis
    Fibrosing Mediastinitis
    Mediastinal Haemorrhage
    Pericardium
    Imaging Pericardial Disease
    Developmental Anomalies
    Congenital Absence of the Pericardium
    Acquired Pericardial Disease
    Pericardial Effusion
    Cardiac Tamponade
    Pericarditis
    Constrictive Pericarditis
    Acknowledgement
    Further Reading
    Online-only References
    12 Pulmonary Infection in Adults
    Chapter Outline
    Types of Pneumonias
    Community-Acquired Pneumonia (CAP)
    Hospital-Acquired Pneumonia (HAP)
    Ventilator-Associated Pneumonia (VAP)
    Health Care-Associated Pneumonia (HCAP)
    Clinical Utility and Limitations of Chest Radiography and CT
    Patterns of Pulmonary Infection
    Complications of Pneumonia
    Integrating Clinical and Imaging Findings
    Lobar Pneumonia
    Most Common Organisms
    Immunocompromised Host
    Endemic in Certain Geographic Areas
    Bronchopneumonia
    Most Common Organisms
    Atypical Pneumonia
    New Emerging Viruses
    Changing Spectrum of HIV Infections: 30 Years Later
    Mycobacterium tuberculosis
    Primary Tuberculosis
    Reactivation and Reinfection Tuberculosis
    Pulmonary Non-Tuberculous Mycobacteria (NTMB)
    Fungal Infection
    Parasitic Infections
    Protozoa
    Amoebiasis
    Nematodes
    Dirofilariasis
    Cestodes
    Echinococcosis (Hydatid Disease)
    Trematodes
    Paragonimiasis
    Further Reading
    Online-only References
    13 irway Disease and Chronic Airway Obstruction
    Chapter Outline
    Introduction
    Tracheal Disorders
    Post-Traumatic Strictures
    Infectious Tracheobronchitis
    Primary Malignant Neoplasms
    Secondary Malignant Neoplasms
    Benign Neoplasms
    ANCA-Associated Granulomatous Vasculitis
    Relapsing Polychondritis
    Tracheobronchial Amyloidosis
    Sarcoidosis
    Inflammatory Bowel Disease
    Tracheobronchopathia Osteochondroplastica
    Sabre-Sheath Trachea
    Tracheobronchomegaly (Mounier–Kuhn Syndrome)
    Tracheobronchomalacia
    Tracheobronchial Fistula and Dehiscence
    Bronchiectasis
    Radiographic Findings
    CT Findings
    Accuracy of CT
    Cystic Fibrosis
    Allergic Bronchopulmonary Aspergillosis (ABPA)
    Dyskinetic Cilia Syndrome
    Broncholithiasis
    Bronchiolitis
    Infective Bronchiolitis
    Inflammatory (Non-Infective) Bronchiolitis
    Obliterative (Constrictive) Bronchiolitis
    Pathological Features
    Radiological Findings
    CT Assessment of Air Trapping
    Chronic Obstructive Pulmonary Disease (COPD)
    Pathological Findings
    Inflammatory Changes in the Airways in COPD
    Radiographic Findings
    CT Findings
    Small Airway Disease
    Emphysema
    Large Airway Disease
    CT Quantitative Analysis of Extent of Disease
    Asthma
    Radiographic Findings
    CT Findings
    Further Reading
    Online-only References
    14 Pulmonary Lobar Collapse:
    Chapter Outline
    Mechanisms and Causes of Lobar Collapse
    Radiographic Considerations
    Direct Signs of Volume Loss
    Indirect Signs of Volume Loss
    Ancillary Features of Lobar Collapse
    Computed Tomography of Lobar Collapse
    Technique
    Utility
    Potential Pitfalls
    Other Imaging Techniques in Lobar Collapse
    Patterns of Lobar Collapse
    Right Upper Lobe Collapse
    Left Upper Lobe Collapse
    Right Middle Lobe Collapse
    Right and Left Lower Lobe Collapse
    Whole Lung Collapse
    Combinations of Lobar Collapse
    Further Reading
    Online-only References
    15 Pulmonary Neoplasms
    Chapter Outline
    Bronchogenic Carcinoma
    Histopathology
    Genetic Factors
    Epidermal Growth Factor Receptor (EGFR)
    Lung Cancer and Other Environmental Factors
    Smoking
    Lung Cancer Screening
    Chest Radiographic Screening
    CT Screening
    Radiation Dose Considerations
    Pulmonary Nodules
    Management of Small Pulmonary Nodules
    Nodule Density
    Other Forms of Nodule Assessment
    Nodule Follow-Up
    PET/CT
    Lung Cancer Staging—the 7Th Edition of the TNM Staging System for Lung Cancer
    Additional Pulmonary Nodules in the Presence of Lung Cancer
    M Descriptors
    Summary
    Imaging Protocols for Lung Cancer Staging
    The Current Standards of CT Technology
    Imaging Features of Bronchogenic Carcinoma
    Peripheral Tumours
    Central Tumours
    Staging Intrathoracic Spread of Bronchial Carcinoma
    Extrathoracic Staging of Lung Cancer
    Pulmonary Sarcoma and Other Primary Malignant Neoplasms
    Benign Pulmonary Tumours
    Hamartoma
    Other Benign Pulmonary Neoplasms
    Leiomyoma
    Benign Lymphoproliferative Disorders
    Lymphocytic Interstitial Pneumonia
    Follicular Bronchiolitis
    Malignant Lymphoproliferative Disorders
    Lymphoma
    Other Findings in Pulmonary Lymphoma
    Leukaemia
    Metastases
    Lymphangitic Carcinomatosis
    Unusual Patterns of Metastatic Cancer
    Endobronchial Metastases
    Further Reading
    Online-only References
    16 High-Resolution Computed Tomography of Interstitial and Occupational Lung Disease
    Chapter Outline
    High-Resolution Computed Tomography Patterns of Diffuse Lung Disease
    Reticular Pattern
    Nodular Pattern
    Ground-Glass Pattern
    Mosaic Attenuation Pattern
    Idiopathic Interstitial Pneumonias
    Usual Interstitial Pneumonia/Idiopathic Pulmonary Fibrosis
    Classic HRCT Findings
    Non-Specific Interstitial Pneumonia
    Classic HRCT Findings
    Cryptogenic Organising Pneumonia
    Respiratory Bronchiolitis–Interstitial Lung Disease and Desquamative Interstitial Pneumonia
    Classic HRCT Findings
    Acute Interstitial Pneumonia/Diffuse Alveolar Damage
    Classic HRCT Findings
    Lymphoid Interstitial Pneumonia
    Classic HRCT Findings
    Idiopathic Pleuroparenchymal Fibroelastosis
    Classic HRCT Findings
    Sarcoidosis
    Lymphadenopathy
    Parenchymal Changes
    High-Resolution Computed Tomography Features
    Classic HRCT Findings
    Hypersensitivity Pneumonitis
    Classic HRCT Findings
    Langerhans Cell Histiocytosis
    Classic HRCT Findings
    Lymphangioleiomyomatosis
    Classic HRCT Findings
    Connective Tissue Diseases
    Rheumatoid Disease
    Classic HRCT Findings
    Sjögren’s Syndrome
    Classic HRCT Findings
    Progressive Systemic Sclerosis (Scleroderma)
    Classic HRCT Findings
    Polymyositis/Dermatomyositis
    Classic HRCT Findings
    Systemic Lupus Erythematosus
    Classic HRCT Findings
    Systemic Vasculitides
    Churg–Strauss Syndrome
    Classic HRCT Findings
    Drug-Induced Lung Disease
    Diffuse Alveolar Damage
    Interstitial Pneumonia
    Organising Pneumonia
    Eosinophilic Pneumonia
    Classic HRCT Findings
    Occupational Lung Disease
    The International Labour Office Classification
    Silicosis/Coal Worker’s Pneumoconiosis
    Classic HRCT Findings
    Asbestos-related Disease
    Benign Pleural Effusions
    Pleural Plaques
    Diffuse Pleural Thickening
    Round Atelectasis
    Asbestosis
    Classic HRCT Findings
    Further Reading
    Books/Book Chapters
    Reviews/Papers
    Online-only References
    17 Thoracic Trauma and Related Topics
    Chapter Outline
    Thoracic Trauma
    Introduction
    Types of Injury
    Diagnostic Approach
    Specific Thoracic Injuries Following Trauma
    Heart
    Mediastinum
    Lung Parenchyma
    Diaphragm
    Thoracic Imaging in the Intensive Care Patient
    Introduction
    Cardiopulmonary Disease
    Atelectasis
    Pulmonary Oedema
    Haemorrhage
    Extra-Pulmonary Air
    Support and Monitoring Apparatus
    Airway
    Post-Surgical Imaging in the Chest
    Introduction
    Post-Pneumonectomy
    Lung Transplantation
    Preoperative Imaging
    Postoperative Imaging
    Surgical Treatment of Emphysema
    Bullectomy
    Further Reading
    Online-only References
    18 Airspace Diseases
    Chapter Outline
    Introduction
    An Approach to the Radiological Diagnosis of Airspace Diseases
    Anatomical Considerations
    Radiological Signs of Airspace Disease
    Pulmonary Oedema
    Chest Radiography in Pulmonary Oedema
    Vascular Changes
    Alveolar Oedema
    Radiographic Differentiation of Cardiogenic and Non-Cardiogenic Pulmonary Oedema
    CT in Pulmonary Oedema
    Diffuse Pulmonary Haemorrhage
    Idiopathic Pulmonary Haemosiderosis
    Antibasement Membrane Antibody Disease (Goodpasture’s Syndrome)
    Wegener’s Granulomatosis (ANCA-Associated Granulomatous Vasculitis)
    Organising Pneumonia
    Eosinophilic Lung Disease
    Simple Pulmonary Eosinophilia (Löffler’s Syndrome)
    Acute Eosinophilic Pneumonia
    Chronic Eosinophilic Pneumonia
    Pulmonary Alveolar Proteinosis
    Alveolar Microlithiasis
    Further Reading
    Books/Book Chapters
    Reviews/Papers
    Online-only References
    19 Cardiac Anatomy and Imaging Techniques
    Chapter Outline
    Normal Chest Radiography
    Cardiac Magnetic Resonance
    Cardiac Axis Imaging Planes
    Body Axes Imaging Planes
    Normal Anatomy on CMR Images
    Computed Tomography Imaging Techniques
    CT Imaging of Ventricles and Myocardial Tissue
    Coronary Arteries by CT
    Valves
    Pulmonary Veins
    Other Structures
    Echocardiography
    Valves
    Acknowledgement
    Further Reading
    MRI
    CT
    Echo
    Online-only References
    20 Congenital Heart Disease:
    Chapter Outline
    Introduction
    Clinical Presentation
    Later Clinical Presentation
    Morphological Description and Sequential Segmental Analysis
    Sequential Segmental Analysis
    Step 1—Atrial Situs
    Step 2—Ventricular Morphology
    Physiological and Functional Assessment
    Non-Invasive Imaging Techniques
    Ultrasound
    Magnetic Resonance Imaging
    Computed Tomography
    Conventional Radiology
    Diagnostic Features
    The Pulmonary Vasculature
    Heart Size, Shape and Position
    Specific Lesions
    Acyanotic Lesions
    Septal Defects
    Abnormalities of the Great Vessels
    Valvular Heart Disease
    Coronary Artery Abnormalities
    Cyanotic Congenital Heart Disease
    Tetralogy of Fallot
    Transposition of the Great Arteries
    Pulmonary Atresia
    Double Outlet Right Ventricle
    Common Arterial Trunk
    Single Ventricles
    Systemic-to-Pulmonary Artery Shunt
    Bidirectional Glenn Circulation
    Conclusion
    Further reading
    Online-only References
    21 Non-ischaemic Acquired Heart Disease
    Chapter Outline
    Role of Imaging
    Chest Radiography
    Echocardiography
    Magnetic Resonance Imaging
    Computed Tomography
    Cardiomyopathies
    Hypertrophic Pattern
    Dilated Phenotype
    Restrictive Phenotype
    Arrhythmogenic Right Ventricular Cardiomyopathy
    Unclassified Cardiomyopathy
    Myocarditis
    Valvular Heart Disease
    Mitral Valve Disease
    Mitral Valve Prolapse
    Mitral Stenosis
    Rheumatic Mitral Valve Disease
    Tricuspid Valve Disease
    Aortic Valve Disease
    Aortic Stenosis
    Aortic Regurgitation
    Prosthetic Cardiac Valves
    Complications of Prosthetic Valves
    Structure Fracture
    Valve Regurgitation
    Thromboembolism
    Tumours of the Heart
    Metastasis
    Primary Cardiac Tumours
    Cardiac Myxoma
    Lipomas
    Rhabdomyomas
    Papillary Fibroelastoma
    Hydatid Disease
    Primary Malignant Tumours of the Heart
    Sarcomas
    Lymphoma
    Pericardial Diseases
    Anatomy
    Pericardial Cysts
    Pericardial Defects
    Pericardial Diverticulum
    Pericardial Effusion
    Pericardial Inflammation
    Constrictive Pericarditis
    Pericardial Masses
    Further Reading
    Online-only References
    22 Ischaemic Heart Disease
    Chapter Outline
    Introduction
    Pathophysiology of Ischaemic Heart Disease
    Coronary Artery Imaging
    Functional Imaging
    Stress Imaging
    Myocardial Infarct Imaging
    Myocardial Viability Imaging
    Imaging of Complications Related to Ischaemic Heart Disease
    Prognosis Assessment in Ischaemic Heart Disease
    Role of Conventional Chest Radiography in Ischaemic Heart Disease
    Differential Diagnosis in Ischaemic Heart Disease
    Further Reading
    Online-only References
    23 Pulmonary Circulation and Pulmonary Thromboembolism
    Chapter Outline
    Pulmonary Circulation
    Pulmonary Circulation Anatomy
    Pulmonary Arteries
    Pulmonary Veins
    Pulmonary Circulation Physiology
    Pulmonary Vascular Patterns
    Pulmonary Venous Hypertension
    Interstitial Oedema (Grade 2)
    Pulmonary Arterial Hypertension
    Pulmonary Arteriovenous Malformations
    Pulmonary Thomboembolic Disease
    Acute Pulmonary Thromboembolism
    Diagnosing Acute Pulmonary Embolism
    Imaging Findings
    Chronic Pulmonary Thromboembolism
    Conclusion
    Acknowledgements
    Further Reading
    Online-only References
    24 The Thoracic Aorta:
    Chapter Outline
    The Normal Aorta
    Diagnostic Aspects
    Acquired Aortic Abnormalities
    Acute Aortic Syndrome
    Aortic Dissection
    Classification
    Intramural Haematoma
    Penetrating Atherosclerotic Ulcer (PAU)
    Traumatic Aortic Injury (TAI)
    Imaging
    Aortic Aneurysms
    Atherosclerotic Aortic Aneurysms
    Abdominal Aneurysms
    Mycotic Aneurysms
    Preoperative Evaluation of Acute Aortic Syndromes
    Impending Aortic Rupture
    Visceral Malperfusion
    Preoperative or Pre-Interventional Evaluation
    Postoperative Evaluation
    Management of Aortic Diseases
    Traumatic Aortic Injury (TAI)
    Aortic Dissection
    Inflammatory Diseases of the Aorta and Mid-Aortic Syndrome
    Mid-Aortic Syndrome
    Aortic Occlusive Disease
    Chronic Aortic Occlusive Disease
    Congenital Aortic Abnormalities
    Vascular Rings
    Double Aortic Arch
    Vascular Rings Associated with Left Aortic Arch
    Coarctation of the Aorta
    Management
    Pseudocoarctation
    Aortic Atresia
    Further Reading
    Online-only References
    C Abdominal Imaging
    25 Current Status of Imaging of the Gastrointestinal Tract:
    Chapter Outline
    The Plain Abdominal Radiograph
    Abnormal Gas Distribution
    Pneumoperitoneum
    Gas in Bowel Wall
    Gas in Retroperitoneum
    Gas in Other Organs
    Dilatation of Bowel
    Gastric Dilatation
    Distinction between Small- and Large-Bowel Dilatation
    Small-Bowel Dilatation
    Large-Bowel Dilatation
    Pseudo-Obstruction
    Abnormal Bowel Wall Pattern
    Small-Bowel Ischaemia
    Large-Bowel Ischaemia
    Inflammatory Bowel Disease
    Pseudomembranous Colitis
    Acute Abdominal Inflammatory Conditions
    Ultrasound in Appendicitis
    Computed Tomography in Appendicitis
    Other Inflammatory Conditions
    Imaging the Abdomen with CT: Radiation Issues
    Automatic Tube Current Modulation
    Iterative Reconstruction Algorithms
    CT Dose Reduction in Clinical Practice
    Further Reading
    Online-only References
    26 The Oesophagus
    Chapter Outline
    Anatomy and Function
    Anatomy (Table 26-1)
    Embryology
    Function
    Examination
    Plain Radiography
    Ultrasound
    Fluoroscopy
    Endoscopy
    CT
    MRI
    Endoscopic Ultrasound
    Radionuclide Radiology Including PET-CT
    Pathological Features
    Oesophageal Cancer
    CT for Oesophageal Cancer
    EUS for Oesophageal Cancer
    PET-CT for Oesophageal Cancer
    Other Oesophageal Neoplasms
    Benign Lesions
    Malignant Lesions
    Hiatus Hernia
    Gastro-Oesophageal Reflux Disease
    Complications of GORD
    Other Varieties of Oesophagitis
    Oesophageal Diverticula
    Motility Disorders
    Achalasia
    Diffuse Oesophageal Spasm
    Neuromuscular Disorders
    Miscellaneous Conditions
    Oesophageal Varices
    Trauma
    Further reading
    Online-only References
    27 The Stomach
    Chapter Outline
    Anatomy
    Radiological Techniques
    Fluoroscopy
    Cross-Sectional Imaging
    Multidetector Computed Tomography (MDCT)
    Magnetic Resonance Imaging (MRI)
    Gastric Pathology
    Inflammatory Disease and Infiltrative Diseases
    Helicobacter pylori and Diseases of the Stomach
    Neoplastic Diseases
    Mucosal Polyps
    Mesenchymal Tumours
    Early Gastric Cancer
    Advanced Gastric Cancer
    Gastric Lymphoma
    Metastatic Disease
    Miscellaneous Conditions
    Positional Abnormalities
    Gastric Volvulus
    Prepyloric Web (Antral Mucosal Diaphragm)
    Hypertrophic Pyloric Stenosis
    Ectopic Pancreas
    The Postoperative Stomach
    Bariatric Surgery for Obesity
    Other Surgeries
    Advances in Gastric Imaging
    Further Reading
    Online-only References
    28 The Duodenum and Small Intestine
    Chapter Outline
    The Duodenum
    Anatomy and Normal Appearances
    Radiological Investigation
    Barium Studies
    Peptic Ulceration
    Postbulbar Ulceration
    Gastric Heterotopia
    Diverticula
    Neoplasms
    Benign Neoplasms
    Other Conditions
    Pancreatitis
    Progressive Systemic Sclerosis
    The Small Intestine
    Anatomy and Normal Appearances
    Radiological Investigation
    Plain Radiographs
    Ultrasound
    Angiography
    The Abnormal Small Intestine
    Crohn’s Disease
    Radiological Appearances
    Coeliac Disease
    Neoplasms
    Malignant Neoplasms
    Benign Neoplasms
    Infections and Infestations
    Mesenteric Adenitis
    Tuberculosis
    Yersiniosis
    Chronic Radiation Enteritis
    Mechanical Small Intestinal Obstruction
    Acute Mesenteric Ischaemia
    Vasculitis
    Occult Gastrointestinal Bleeding
    Diverticula and Blind Loops
    Jejunal Diverticula
    Ileal Diverticula
    Neuromuscular Disorders
    Nodular Lymphoid Hyperplasia and Immunoglobulin Deficiency
    Whipple’s Disease
    Intestinal Lymphangiectasia
    Eosinophilic Gastroenteritis
    Mastocytosis
    Angio-Oedema
    Amyloidosis
    Acquired Immune Deficiency Syndrome
    Behçet’s Disease
    Graft-Versus-Host Disease
    Non-steroidal Anti-Inflammatory Drug Enteritis
    Further Reading
    Online-only References
    29 The Large Bowel
    Chapter Outline
    Anatomy
    Radiological Investigation
    Tumours
    Polyps
    Polyposis Syndromes
    Radiographic Features of Polyps
    Colorectal Cancer
    Colon Cancer
    Rectal Cancer
    Anal Cancer
    Appendix Tumours
    Lymphoma
    Secondary Cancers
    Diverticulitis
    Epiploic Appendagitis
    Colitis
    Imaging Features of Colitis
    Inflammatory Bowel Disease
    Differential Features
    Carcinoma in Colitis
    Other Common Causes of Colitis
    Ischaemic Colitis
    Radiation Colitis
    Behçet’s Syndrome
    Infectious Colitis
    Pseudomembranous Colitis
    Neutropenic Colitis
    Parasitic Colitis
    Tuberculosis
    Amoebiasis
    Acquired Immunodeficiency Syndrome
    Defunctioned Colon
    Acute Fulminant Colitis
    Perforation
    Miscellaneous Conditions
    Large-Bowel Strictures
    Pseudodiverticula
    Appendicitis
    Lipomatous Disorders of the Large Bowel
    Pneumatosis Coli
    Volvulus
    Intussusception
    Endometriosis
    Retrorectal Lesions
    Functional Disorders of the Anorectum
    Anal Fistula
    Further Reading
    Online-only References
    30 Imaging of the Peritoneum, Mesentery and Omentum
    Chapter Outline
    Anatomical Considerations
    Introduction
    Peritoneal Spaces
    Supramesocolic Space
    Inframesocolic Space
    Peritoneal Reflections
    The Mesenteries
    The Omentum
    Pathological Considerations
    Ascites
    Intraperitoneal Air
    Developmental/Congenital Anomalies
    Rotational Anomaly
    Developmental Defects
    Mesenteric Cysts
    Infections–Inflammations
    Tuberculosis
    Hydatid Disease
    Crohn’s Disease
    Mesenteric Lymphadenitis
    Acute Pancreatitis
    Whipple’s Disease
    Mesenteric Panniculitis–Sclerosing Mesenteritis
    Sclerosing Peritonitis
    Non-inflammatory Oedema
    Epiploic Appendagitis
    Omental Infarction
    Neoplastic Diseases
    Neoplastic Diseases of Peritoneum
    Direct Spread Along Mesenteric and Ligamentous Attachments
    Primary Neoplasms
    Neoplastic Diseases of Mesentery
    Primary Neoplasms
    Neoplastic Diseases of the Omentum
    Further reading
    Online-only References
    31 The Liver and Spleen
    Chapter Outline
    Liver
    Anatomy
    Subdivisions (Fig. 31-2)
    Lobar Agenesis/Atrophy (Figs. 31-3 and 31-4)
    Liver Imaging Techniques
    Plain Radiography
    Ultrasound
    Technique
    Computed Tomography
    Technique (Fig. 31-9)
    Normal
    Magnetic Resonance Imaging
    Techniques (Fig. 31-11)
    Intravenous Contrast Agents (Fig. 31-12)
    Scintigraphy
    Technique
    Angiography
    Diffuse Disease
    Benign Diffuse Disease
    Hepatic Steatosis
    Viral Hepatitis
    Wilson’s Disease
    Malignant Diffuse Disease
    Focal Disease
    Calcification
    Parenchymal Gas
    Benign Cystic Lesions
    Cysts
    Hydatid Disease
    Malignant Cystic Lesions
    Metastases
    Benign Solid Lesions
    Haemangioma
    Atypical Haemangiomas
    Hepatic Adenoma
    Focal Fat
    Biliary Hamartomas (Fig. 31-44)
    Malignant Solid Lesions
    Hepatocellular Carcinoma
    Fibrolamellar Carcinoma (FLC) (Fig. 31-53)
    Hepatoblastoma
    Metastases
    Vascular Lesions
    Budd–Chiari Syndrome
    Veno-Occlusive Disease
    Arterioportal Shunts
    Intrahepatic Portosystemic Shunts
    Hepatic Trauma
    Liver Transplantation
    Background and Indications
    Perioperative Imaging
    Liver Biopsy
    Liver Biopsy, Aspiration and Drainage
    Spleen
    Anatomy
    Congenital Variations
    Accessory Spleen or Splenunculus (Fig. 31-74)
    Acquired Diseases
    Trauma (Fig. 31-76)
    Infarction (Figs. 31-78 and 31-79)
    Benign Lesions
    Cysts (Fig. 31-80)
    Malignant Lesions
    Angiosarcoma (Fig. 31-83)
    Lymphoma (Fig. 31-84)
    Metastases (Fig. 31-85)
    Other Problems
    Portal Hypertension/Splenic Vein Thrombosis
    Sarcoidosis
    Haemosiderosis
    Further Reading
    Online-only References
    32 The Biliary System
    Chapter Outline
    Biliary Anatomy
    Gallbladder Anatomical Variants
    Methods of Investigation
    Ultrasound
    Computed Tomographic Cholangiography
    Magnetic Resonance Cholangiopancreatography
    Endoscopic Retrograde Cholangiopancreatography
    Percutaneous Transhepatic Cholangiography
    Intraoperative Cholangiography
    T-Tube Cholangiography
    Hepatobiliary Scintigraphy
    Endoscopic Ultrasound
    Disorders of the Gallbladder
    Gallbladder Stones
    Sludge
    Milk of Calcium Bile
    Cholecystitis
    Acute Calculous Cholecystitis
    Emphysematous Cholecystitis
    Acalculous Cholecystitis
    Gallbladder Mucocele
    Gallbladder Fistulae
    Porcelain Gallbladder
    Adenomyomatous Hyperplasia
    Gallbladder Polyps
    Gallbladder Carcinoma
    Gallbladder Metastases and Lymphoma
    Role of Radiology in Investigation of Jaundice
    Benign Bile Duct Pathology
    Choledocholithiasis
    Ultrasound
    Hepatolithiasis
    Benign Biliary Strictures
    Postoperative Strictures
    Primary Sclerosing Cholangitis
    Pancreatitis
    Acute Bacterial Cholangitis
    Parasitic Infections
    Ascaris lumbricoides
    Biliary Leaks and Bile Duct Injuries
    Biliary Cystic Disease
    Neoplastic Bile Duct Pathology
    Cholangiocarcinoma
    Metastases and Lymphoma
    Pancreatic and Ampullary Tumours
    Miscellaneous Biliary Tumours
    Liver Atrophy
    Lobar or Segmental Duct Obstruction
    Haemobilia
    Interventional Techniques
    Percutaneous Cholecystostomy
    Percutaneous Transhepatic Biliary Catheterisation
    Malignant Disease
    Hilar Strictures—Special Considerations
    Benign Disease
    Percutaneous Transjejunal Biliary Intervention
    Biopsy Techniques
    Further Reading
    Online-only References
    33 The Pancreas
    Chapter Outline
    Embryology
    The Normal Pancreas
    Congenital Anomalies
    Pancreas Divisum
    Annular Pancreas
    Pancreatic Agenesis, Hypoplasia and Ectopic Pancreas
    Acute Pancreatitis
    Imaging in Acute Pancreatitis
    Interstitial Oedematous Pancreatitis
    Necrotising Pancreatitis
    Pancreatic and Peripancreatic Collections
    Pseudocyst
    Acute Necrotic Collection (ANC)
    Walled-Off Necrosis (WON)
    Pseudocysts
    Vascular Complications
    Gastrointestinal Involvement
    Chronic Pancreatitis
    Groove Pancreatitis
    Autoimmune Pancreatitis
    Pancreatic Neoplasms
    Ductal Adenocarcinoma
    Imaging Techniques
    Imaging Appearances
    Local Staging
    Follow-Up
    Neuroendocrine Pancreatic Tumours (NET)
    Functioning Tumours
    Non-functioning NETs
    Cystic Masses
    What To Do With Small Incidental Cystic Lesions
    Rare Pancreatic Neoplasms
    Multisystem Diseases with Involvement of the Pancreas
    Cystic Fibrosis
    Von Hippel–Lindau Disease
    Polycystic Kidney Disease
    Osler–Weber–Rendu Disease
    Trauma
    Pancreatic Transplant Imaging
    Interventional Radiology
    Biopsy of Pancreatic Lesions
    Drainage of Pancreatic/Peripancreatic Fluid Collections
    Further Reading
    Online-only References
    34 Common Uroradiological Referrals:
    Chapter Outline
    Haematuria
    Renal Tract Calcifications
    Imaging of Renal and Ureteric Stones
    Imaging of Renal and Ureteric Tumours
    Risk Stratification of Patients with Haematuria for Triage to Computed Tomography
    Imaging Features of Urothelial Tumours on Computed Tomography
    Loin Pain
    Imaging of Patients with Loin Pain
    Radiography
    Computed Tomography
    Useful Signs on Unenhanced CT and Potential Pitfalls
    Renal Failure
    Chronic Renal Failure
    Autosomal Dominant Polycystic Kidney Disease (Adult Polycystic Kidney Disease)
    Tuberous Sclerosis
    Acquired Cystic Kidney Disease (ACKD)
    Renovascular Disease
    Contrast Medium-Induced Nephrotoxicity
    Nephrogenic Systemic Fibrosis
    Infection
    Acute Pyelonephritis
    Imaging of Acute Pyelonephritis
    Renal and Perirenal Abscess
    Imaging of Renal and Perirenal Abscess
    Emphysematous Pyelonephritis
    Imaging of Emphysematous Pyelonephritis
    Xanthogranulomatous Pyelonephritis (XGP)
    Imaging of XGP
    Pyonephrosis
    Imaging of Pyonephrosis
    Chronic Pyelonephritis
    Imaging of Chronic Pyelonephritis
    Renal Tuberculosis
    Imaging of Renal Tuberculosis
    Cystitis
    Imaging of Cystitis
    Prostatitis
    Acute Bacterial Prostatitis and Prostatic Abscess
    Online-only References
    35 The Urinary Tract:
    Chapter Outline
    Introduction
    Anatomy of the Urinary Tract
    Embryology
    Normal Urinary Tract Anatomy
    Congenital Abnormalities of the Urinary Tract
    Renal
    Ureter and Pelvis
    Bladder and Urethra
    Techniques
    Conventional Radiography
    Intravenous Urography (IVU)/Excretory Urography
    Retrograde Urography
    Retrograde Urethrography and Voiding Cystourethrogram
    Ultrasound
    Nuclear Medicine
    CT
    MRI
    Radiation Issues
    Radiation Exposure from Medical Imaging
    Conventional Radiography
    CT
    Conclusion
    Further Reading
    Online-only References
    36 Renal Masses:
    Chapter Outline
    Methods of Analysis
    Plain Abdominal Radiography
    Intravenous Urography
    Radionuclide Imaging
    Ultrasound
    Computed Tomography
    MRI
    Renal Arteriography
    Needle Aspiration and Biopsy
    Non-Neoplastic Renal Masses
    Pathological Renal Masses
    Renal Cysts
    Serous Renal Cyst
    ‘Complicated Cysts’
    Parapelvic and Peripelvic Cysts
    Inflammatory Masses
    Renal Abscesses
    Vascular Masses
    Haematomas
    Intrarenal Vascular Masses
    Angiomyolipomas
    Focal Hydronephrosis
    Renal Sinus Lipomatosis
    Non-Renal Masses
    Neoplastic Renal Masses
    Benign
    Adenoma and Oncocytoma
    Malignant
    Parenchymal
    Non-Parenchymal
    Further Reading
    Online-only References
    37 Renal Transplantation:
    Chapter Outline
    History of Transplant
    Surgical Technique
    Technique of Examination
    Vascular Complications: Early
    Infarction
    Acute Rejection
    Acute Tubular Necrosis
    Non-vascular Complications
    Urinoma
    Lymphocele
    Ureteric Strictures
    Renal Calculi
    Vascular Complications: Intermediate to Late
    Renal Artery Stenosis
    Chronic Rejection
    Cancer and Transplant
    Infection and Renal Transplantation
    Use of Isotope Studies and Renal Transplant
    Renal Transplant Biopsy
    Radiological Evaluation of Potential Donor Kidneys
    Further Reading
    Online-only References
    38 Urothelial Cell Cancer, Upper Tract and Lower Tract
    Chapter Outline
    Upper Tract Urothelial Carcinoma
    Definition
    Epidemiology
    Risk Factors
    Identification of Prognostic Factors
    Management
    Biopsy
    Imaging Upper Tract Urothelial Carcinoma
    Definition of CT Urography
    Quality Control
    Diagnostic Imaging Strategies for UTUC
    Problems and Solutions
    Conclusions and Summary
    Bladder Cancer
    Introduction
    Classification of Urothelial Cancers
    By Growth Pattern
    By Grade
    Clinical Detection
    Imaging Detection
    Technique of CT Urography and MR Urography
    CT and MR Urographic Appearance of Bladder Cancers
    Sensitivity and Specificity of CT and MR Urography in Detecting Bladder Cancers
    Risks of CT and MR Urography
    Staging
    Imaging for Local Staging of Bladder Cancer
    Imaging for Detection of Regional and Distant Metastatic Disease
    Upper Tract Evaluation
    Treatment and Follow-Up
    Clinical and Imaging Follow-up of Patients after Topical Treatment of Bladder Cancer
    Imaging Follow-up of Patients after Cystectomy
    Uncommon Bladder Neoplasms
    Squamous Cell Carcinomas
    Cancers in Bladder Diverticula
    Benign Bladder Lesions
    Further Reading
    Upper Tract Urothelial Cancer
    Bladder Cancer
    Online-only References
    39 Prostate
    Chapter Outline
    Multi-Parametric Prostate MRI
    Introduction
    Anatomy
    Histology
    MR Imaging
    T2-Weighted MR Imaging
    T1-Weighted MR Imaging
    DCE MR Imaging
    DWI MR Imaging
    MRSI
    Local Staging
    Aggressiveness
    1.5 Versus 3.0
    Recurrence
    Biopsy
    Protocols
    Detection and Localisation of Primary or Recurrent PCa
    Staging of PCa
    Further Reading
    Online-only References
    40 Male Genitourinary Tract
    Chapter Outline
    Methods of Examination
    Anatomy
    Scrotal Masses
    Testicular Masses
    Malignant Testicular Pathology
    Staging Testicular Malignancy
    Non-Primary Testicular Malignancies, Lymphoma and Leukaemia
    Non-Focal Testicular Abnormalities
    Extratesticular Scrotal Lesions
    Hypoechoic Lesions
    Solid Extratesticular Lesions
    Imaging of Male Sexual Dysfunction
    Subfertility with Normal Sexual Function
    Erectile Failure
    Evaluation of the Soft Tissues of the Penis
    Further Reading
    Online-only References
    41 Gynaecological Cancer
    Chapter Outline
    Imaging Techniques
    Ultrasound
    Computed Tomography
    Magnetic Resonance Imaging
    Positron Emission Tomography/Computed Tomography
    Endometrial Carcinoma
    Detection, Diagnosis and Staging
    Ultrasound
    Magnetic Resonance Imaging
    Positron Emission Tomography/ Computed Tomography
    Recommended Imaging Approach
    Carcinoma of the Cervix
    Detection, Diagnosis and Staging
    Ultrasound
    Magnetic Resonance Imaging
    Positron Emission Tomography/ Computed Tomography
    Recommended Imaging Approach
    Ovarian Carcinoma
    Detection, Diagnosis and Staging
    Ultrasound
    Magnetic Resonance Imaging
    Positron Emission Tomography/ Computed Tomography
    Recommended Imaging Approach
    Conclusion
    Acknowledgements
    Further Reading
    Online-only References
    42 Benign Gynaecological Disease
    Chapter Outline
    Imaging Techniques
    Ultrasound
    Computed Tomography
    Magnetic Resonance Imaging
    Hysterosalpingography and Fallopian Tube Catheterisation
    Sonohysterography
    Congenital Anomalies of the Female Genital Tract
    Müllerian Duct Anomalies
    Class I: Uterine Agenesis or Hypoplasia
    Class V: Septate Uterus
    Class VII: Diethylstilbestrol Related
    Vaginal Anomalies
    Imaging of Ambiguous Genitalia
    Benign Uterine Conditions
    Fibroids
    Ultrasound
    Computed Tomography
    Endometrial Polyps
    Endometrial Hyperplasia
    Adenomyosis
    Ultrasound
    Pelvic Pain
    Endometriosis
    Ultrasound
    Pelvic Inflammatory Disease
    Ultrasound
    Computed Tomography
    Pelvic Varices
    Benign Ovarian Conditions
    Functional Ovarian Cysts
    Polycystic Ovaries
    Magnetic Resonance Imaging
    Benign Tumours of the Ovary
    Epithelial Tumours
    Germ Cell Tumours
    Stromal Cell Tumours
    Ovarian Torsion
    Vaginal Cysts
    Further Reading
    Online-only References
    43 Genitourinary Tract Trauma
    Chapter Outline
    Introduction
    Renal Injury
    Clinical Aspects
    CT Technique for Renal Injury
    Grading of Renal Injury and Implications for Management
    CT of Grade I–III Renal Injury
    CT of Grade IV Renal Injury
    CT of Grade V Injury
    Penetrating Renal Trauma
    Intervention in Renal Injury
    Ureteral Injury
    Bladder Injury
    Diagnostic Technique
    Classification
    Urethral Injury
    Scrotal Injury
    Penile Injuries
    Further Reading
    Online-only References
    44 Adrenal Imaging
    Chapter Outline
    The Adrenal Glands
    Anatomy and Physiology
    Anatomy
    Incidentally Detected Adrenal Mass
    Computed Tomography (CT)
    Magnetic Resonance Imaging
    Incidentally Detected Non-Functioning Adrenal Masses
    Adrenal Cysts
    Myelolipoma
    Imaging Functional Disorders of the Adrenal Gland
    Hyperfunctioning Adrenal Cortical Disorders
    Hyperfunctioning Adrenal Medullary Disorders
    Adrenal Hypofunction (Addison’s Disease)
    Conclusion
    Further Reading
    Online-only References
    Subject Index
    A
    B
    C
    D
    E
    F
    G
    H
    I
    J
    K
    L
    M
    N
    O
    P
    Q
    R
    S
    T
    U
    V
    W
    X
    Y
    Z
    GRAINGER & ALLISON’S DIAGNOSTIC RADIOLOGY A Textbook of Medical Imaging: Volume II
    Grainger & Allison’s Diagnostic Radiology
    Copyright page
    Table of Contents
    Preface
    List of Section Editors
    List of Contributors
    D The Musculoskeletal System
    45 Imaging Techniques and Fundamental Observations for the Musculoskeletal System
    Chapter Outline
    Introduction
    Imaging Techniques Available
    Radiography
    Benefits
    Advances and Variations
    Ultrasound (US)
    Benefits
    Computed Tomography (CT)
    Benefits
    Magnetic Resonance Imaging (MRI)
    Benefits
    Nuclear Medicine
    Benefits
    Normal Imaging Appearances
    Radiography
    Bones and Joints
    Ultrasound
    Bone and Joints
    Computed Tomography
    Bone
    MRI
    Bone and Joints
    Soft Tissues
    Specific Radiological Scenarios
    Soft-tissue Calcification and Ossification
    Dystrophic Calcification
    Calcium Pyrophosphate Dihydrate Deposition Disease (CPPD)
    Gas in the Soft Tissues
    Periosteal Reaction
    Further Reading
    Online-only References
    46 Internal Derangements of Joints:
    Chapter Outline
    Introduction
    The Shoulder
    Rotator Cuff Disease
    GHJ Instability
    Superior Labral Tears
    The Acromioclavicular Joint
    The Sternoclavicular Joint
    The Elbow
    Tendons
    Bone and Cartilage
    Ligaments
    Hand and Wrist
    Bone
    Wrist Ligaments
    Triangular Fibrocartilage
    Wrist Tendons
    Median Nerve
    UCL of Thumb
    The Hip
    Labrum and Cartilage
    Muscle and Tendon
    Bone
    Bursae
    The Knee
    Menisci
    Anterior Cruciate Ligament
    Posterior Cruciate Ligament
    Medial Collateral Ligament
    Lateral Collateral Ligament Complex and Posterolateral Corner
    The Extensor Mechanism and Patellofemoral Joint
    Bone and Cartilage
    Bursae
    The Ankle and Foot
    Ligaments
    Tendons
    Bone
    Tarsal Coalition
    Other Soft-Tissue Abnormalities
    Further Reading
    Online-only References
    47 Bone Tumours (1):
    Chapter Outline
    General Characteristics of Bone Tumours
    Age at Presentation
    Radiological Assessment of Bone Tumours
    Location
    Periosteal Reaction2
    Matrix Mineralisation
    Benign Bone Tumours
    Cartilage Tumours
    Osteochondroma
    (En)Chondroma
    Chondroblastoma
    Chondromyxoid Fibroma
    Osteogenic Tumours
    Osteoid Osteoma (OO)
    Osteoblastoma
    Fibrogenic Tumours
    Desmoplastic Fibroma
    Fibrohistiocytic Tumours
    Fibrous Cortical Defect
    Benign Fibrous Histiocytoma
    Giant Cell Tumour
    Giant Cell Tumour
    Vascular Tumours
    Haemangioma
    Smooth Muscle Tumours
    Leiomyoma
    Lipogenic Tumours
    Intraosseous Lipoma
    Neural Tumours
    Schwannoma of Bone
    Miscellaneous Lesions
    Aneurysmal Bone Cyst
    Osteofibrous Dysplasia
    Langerhans Cell Histiocytosis (LCH)
    Erdheim–Chester’s Disease
    Further Reading
    Online-only References
    48 Bone Tumours (2):
    Chapter Outline
    Introduction
    Bone Metastases
    Distribution of Bone Metastases
    Diagnosis of Bone Metastases
    Clinical
    Radiological Investigation of Bone Metastases
    Bone Metastases in Children
    Primary Malignant Neoplasms of Bone
    Chondroid Origin
    Chondrosarcoma
    Other Chondrosarcoma Variants
    Osteoid Origin
    Osteosarcoma
    Fibrous Origin
    Marrow Tumours
    Ewing’s Sarcoma and Primitive Neuroectodermal Tumour (PNET)
    Imaging Features
    Notochordal Origin
    Chordoma
    Miscellaneous Tumours
    Malignant Vascular Tumours
    Further Reading
    Online-only References
    49 Soft Tissue Tumours
    Chapter Outline
    Introduction
    Imaging Characterisation of Soft Tissue Masses
    Radiographs
    Computed Tomography (CT)
    Ultrasound (US)
    Magnetic Resonance Imaging (MRI)
    World Health Organization Classification of Soft Tissue Tumours
    Lipomatous (Adipocytic) Tumours
    Lipoma
    Other Benign Adipocytic Tumours
    Atypical Lipomatous Tumour/Well-Differentiated Liposarcoma (ALT/WDL)
    Fibroblastic/Myofibroblastic Tumours
    Nodular Fasciitis (NF)
    Elastofibroma (EF)
    So-Called Fibrohistiocytic Tumours
    Pigmented Villonodular Synovitis (PVNS) and Giant Cell Tumour of the Tendon Sheath (GCTTS)
    Vascular Tumours
    Haemangioma
    Chondro-Osseous Tumours
    Soft Tissue Chondromas
    Tumours of Uncertain Differentiation
    Myxoma
    Soft Tissue Sarcomas (STSs)
    Tumours of Nerves
    Benign Nerve Sheath Tumours
    Malignant Nerve Tumours
    Non-Neoplastic Tumour Mimics
    Accessory Muscles
    Infection/Inflammation
    Further Reading
    Online-only References
    50 Metabolic and Endocrine Skeletal Disease
    Chapter Outline
    Bone Physiology and Pathophysiology
    Bone Cells
    Bone Formation and Turnover
    Bone Growth and Development
    Osteoporosis
    Definition and Epidemiology
    Radiological Features
    Spine in Osteoporosis
    Vertebroplasty and Kyphoplasty
    Osteoporotic Fractures
    Aetiology
    Regional Osteoporosis
    Osteogenesis Imperfecta
    Type I
    Type III (Severe Progressive)
    Quantitative Assessment of the Skeleton
    Dual Energy X-ray Absorptiometry (DXA)
    Quantitative Computed Tomography (QCT)
    Quantitative Ultrasound
    Vertebral Morphometry
    Parathyroid Disorders
    Hyperparathyroidism
    Primary Hyperparathyroidism
    Hypoparathyroidism
    Aetiology
    Radiological Abnormalities
    Pseudohypoparathyroidism (PHP)
    Radiographic Abnormalities
    Pseudo-Pseudohypoparathyroidism (PPHP)
    Rickets and Osteomalacia
    Vitamin D Deficiency
    Genetic Disorders of Vitamin D Metabolism
    Radiological Appearances
    Azotaemic Osteodystrophy
    Renal Tubular Defects
    Other Causes of Rickets and Osteomalacia (Not Related to Vitamin D Deficiency or Hypophosphataemia)
    Hypophosphatasia
    Other Metabolic Bone Disorders
    Osteopetrosis
    Autosomal Recessive Lethal Type of Osteopetrosis
    Benign, Autosomal Dominant Type of Osteopetrosis (Albers-Schönberg Disease)
    Hyperphosphatasia
    Miscellaneous
    Vitamin D Intoxication
    Hypervitaminosis A
    Fluorosis
    Other Endocrine Diseases
    Cushing’s Disease
    Further Reading
    Online-only References
    51 Arthritis
    Chapter Outline
    Imaging of Joint Disease
    Plain Radiographic Interpretation; General Principles
    Soft-Tissue Swelling
    Bone Alignment
    Distribution of Joint Involvement
    Osteoarthritis
    Primary Osteoarthritis
    Secondary Osteoarthritis
    Radiographic Findings
    Radiographic Changes at Specific Joints
    Knee
    Hands and Wrists
    Advanced Imaging
    Erosive (Inflammatory) Osteoarthritis
    The Inflammatory Arthritides
    Rheumatoid Arthritis
    Radiographic Features
    Radiographs in Treated Inflammatory Disease
    Sero-Negative Arthritis
    Ankylosing Spondylitis
    Psoriatic Arthritis
    Reactive Arthritis
    The Crystal Arthritides
    Gout
    Calcium Pyrophosphate Dihydrate (CPPD) Crystal Deposition Disease
    Connective Tissue Disease
    Scleroderma
    Rheumatic Fever (Jaccoud’s Arthropathy)
    Miscellaneous Joint Disease
    Diffuse Idiopathic Skeletal Hyperostosis (DISH)
    Haemophilic Arthropathy
    Neuropathic Arthropathy
    Synovial (Osteo)-Chondromatosis
    Pigmented Villonodular Synovitis (PVNS)
    Lipoma Arborescens
    Amyloid
    Sarcoid
    Hypertrophic Pulmonary Osteoarthropathy (HPOA)
    Multicentric Reticulohistiocytosis
    Haemochromatosis
    Further Reading
    Online-only References
    52 Appendicular and Pelvic Trauma
    Chapter Outline
    General Considerations
    Describing Fracture Types
    The Shoulder
    The Acromio-Clavicular Joint
    The Elbow
    Children
    Adults
    The Wrist
    Radius and Ulna
    Children
    Carpal Injuries
    Injuries of the Metacarpals and Phalanges
    Pelvic and Acetabular Fractures
    Introduction
    Pelvic Ring Fractures
    Anatomy
    Classification
    Acetabular Fractures
    Anatomy
    Elemetary Patterns
    Avulsion Injuries
    Insufficiency and Stress Fractures
    Pathological Fractures
    The Hip
    The Knee
    The Ankle
    Foot Injuries
    Further Reading
    Online-only References
    53 Bone, Joint and Spinal Infection
    Chapter Outline
    Introduction
    Epidemiology
    Classification
    Paediatric Musculoskeletal Infections
    Pathophysiology
    Clinical Features
    Investigations and Management
    Plain Radiographs
    Nuclear Medicine
    Chronic Recurrent Multifocal Osteomyelitis (CRMO)
    SAPHO Syndrome
    Sclerosing Osteomyelitis of Garré
    Necrotising Fasciitis
    Adult Musculoskeletal Infections
    Pathogenesis
    Clinical Features
    Investigations and Management
    Plain Radiographs
    Ultrasound
    Magnetic Resonance Imaging
    Nuclear Medicine
    Osteomyelitis Secondary to Prosthetic Devices
    Diabetic Foot
    Plain Radiography
    Magnetic Resonance Imaging
    Septic Arthritis
    Musculoskeletal Tuberculosis
    Pathogenesis
    Investigations (Table 53-2)
    Plain Radiography
    Magnetic Resonance Imaging
    Unusual Musculoskeletal Infections
    Atypical Mycobacterial Musculoskeletal Infections
    Hydatid Disease
    Bone Infections in Sickle Cell Disease
    Musculoskeletal Fungal Infections
    Musculoskeletal Infections in HIV Patients
    Differential Diagnosis
    Management
    Spinal Infection
    Vertebral Osteomyelitis
    Pyogenic Vertebral Osteomyelitis
    Symptoms
    Treatment
    Tuberculous Vertebral Osteomyelitis
    Plain Radiographs
    Unusual Spine Infections
    Further Reading
    Online-only References
    E The Spine
    54 Imaging Techniques and Anatomy
    Chapter Outline
    Anatomy
    Osseous Elements
    Vertebral Body
    Neural Arch
    Spinous and Transverse Processes
    Joints
    Facet Joints
    Intervertebral Disc—Symphysis
    Ligaments
    Longitudinal Ligaments
    Interconnecting Ligaments
    Neural Structures—Spinal Cord, Spinal Nerves, Dura Mater
    Vascular Structures
    Craniocervical Junction
    Imaging Techniques
    Plain Radiography
    Myelography
    Spinal Angiography
    Computed Tomography
    Magnetic Resonance Imaging
    Spin-Echo T1-Weighted Imaging
    Spin-Echo and Fast Spin-Echo T2-Weighted Imaging
    Short Tau Inversion Recovery
    Fluid-Attenuated Inversion Recovery
    Further Reading
    Online-only References
    55 Degenerative Disease of the Spine
    Chapter Outline
    Introduction
    Degenerative Disc Disease
    Nomenclature and Classification
    Age-related Changes in the Intervertebral Disc
    Degenerative Disc Disease
    Annular Tears
    Disc Heriation
    Spontaneous Regression of Disc Herniation
    Vertebral Endplates and Bone Marrow Changes
    Pathology of the Posterior Elements
    Osteoarthritis of the Facet Joints
    Associated Soft-Tissue Changes
    Degenerative Cysts Arising from the Facet Joints
    Cysts of the Ligamentum Flavum
    Degenerative Changes of the Neural Arch
    Neural Arch Intervertebral Neoarthrosis
    Degenerative Spondylolisthesis
    Degenerative Spinal Stenosis
    Degenerative Spinal Canal Stenosis
    Degenerative Foraminal Stenosis
    Further Reading
    Online-only References
    56 Spinal Tumours
    Chapter Outline
    Radiological Investigations in Spinal Tumours
    Plain Film Radiography
    Computed Tomography
    Magnetic Resonance Imaging
    Diffusion-Weighted Imaging
    Bone Scintigraphy
    Positron Emission Tomography
    Classification of Spinal Tumours
    Intramedullary Tumours
    Ependymoma
    Myxopapillary Ependymoma
    Haemangioblastoma
    Ganglioglioma
    Less Frequent Intramedullary Tumours
    Spinal Cord Tumour Mimics
    Intradural Extramedullary Tumours
    Nerve Sheath Tumours: Schwannoma and Neurofibroma
    Metastases
    Less-Frequent Extramedullary Tumours
    Extradural Tumours
    Metastatic Spine Disease
    Primary Vertebral Tumours
    Benign Primary Vertebral Tumours
    Vertebral Haemangioma
    Osteoid Osteoma/Osteoblastoma
    Osteoblastoma
    Eosinophilic Granuloma
    Benign Notochordal Cell Tumours
    Locally Aggressive Primary Vertebral Tumours
    Primary Malignant Vertebral Tumours
    Multiple Myeloma and Plasmacytoma
    Chondrosarcoma
    Osteosarcoma
    Further Reading
    Online-only References
    57 Non-tumoural Spinal Cord Lesions
    Chapter Outline
    Inflammatory Disease
    Multiple Sclerosis
    Acute Disseminated Encephalomyelitis
    Acute Transverse Myelitis
    Neuromyelitis Optica
    Systemic Lupus Erythematosus
    Sarcoidosis
    Demyelinating Polyneuropathies
    Guillain–Barré Syndrome
    Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
    Vascular Diseases
    Spinal Dural Arteriovenous Fistula (SDAVF)
    Spinal Arteriovenous Malformations (SAVMs)
    Spinal Cord Cavernous Malformation (SCCM)
    Spinal Cord Infarction
    Spinal Cord Vasculitis
    Spinal Cord Infection
    Developmental and Cyst-Like Lesions
    Intramedullary Lipoma
    Lipomyelomeningodysplasias
    Diastematomyelia
    Neuroenteric and Other Developmental Cysts
    Chiari Malformations
    Chiari Type I Lesion (Cerebellar Ectopia)
    Meningoceles
    Anterior Sacral Meningocele
    Anterior Thoracic Meningocele with Ventral Herniation of Spinal Cord
    Intraspinal Arachnoid Cyst
    Syringomyelia
    Neurodegenerative and Metabolic Diseases
    Motor Neuron Disease (MND)
    Spinal Muscular Atrophy (SMA)
    Spinocerebellar Ataxia
    Friedreich’s Ataxia (FRDA)
    Subacute Combined Degeneration of the Spinal Cord (SCD)
    Further Reading
    Online-only References
    58 Postoperative Spine
    Chapter Outline
    Introduction
    Principles of Spinal Surgery
    Imaging Techniques in Postoperative Spine
    Intraoperative and Perioperative Complications
    Early Complications
    Late Complications
    Failed Back Surgery Syndrome
    Image-Guided Percutaneous Cement Bone Augmentation
    Further Reading
    Online-only References
    59 pinal Trauma
    Chapter Outline
    Clinical Aspects
    Imaging Techniques and Evaluation
    Cervical Spine
    Conventional Radiographs
    CT
    Thoracolumbar Spine
    Conventional Radiographs
    Specific Injury Patterns
    Cervical Spine
    Atlanto-Occipital Dissociation
    C2 Injuries
    Hyperflexion Rotation Injury
    Thoracic and Lumbar Spine
    Classification Systems
    Fracture Dislocation
    The Rigid Spine
    Neurological Injury
    Spinal Cord
    Brachial Plexus Injury
    Further Reading
    Online-only References
    F Neuroimaging
    60 Overview of Anatomy, Pathology and Techniques; Aspects Related to Trauma
    Chapter Outline
    Overview of Anatomy, Pathology and Techniques
    Anatomy of the Brain and Vascular System
    Embryology
    Cerebral Cortex, Lobar Anatomy and Deep Grey Matter Structures
    White Matter Centre
    Limbic System, Hypothalamus and Pituitary Gland
    Ventricular System and Subarachnoid Space
    Cerebellum
    Cerebral Vasculature
    Anterior Circulation
    Intracranial Veins
    Techniques for Imaging the Brain and Cerebral Vasculature
    Computed Tomography
    Magnetic Resonance Imaging
    Nuclear Medicine
    Vascular Imaging Techniques
    Conventional Catheter Digital Subtraction Angiography
    Computed Tomography Angiography (CTA)
    Trauma to the Skull and Brain
    Head Injury
    Skull Fractures
    Traumatic Haemorrhage
    Primary Cerebral Damage in Closed Head Injury
    Superficial Primary Cerebral Damage
    Primary Brainstem Injuries
    Other Types of Intracranial Haemorrhage after Closed Head Injury
    Subarachnoid Haemorrhage
    Secondary Cerebral Damage with Closed Head Injury
    Other Complications with Closed Head Injuries
    Penetrating Head Injuries
    Further Reading
    Online-only References
    61 Benign and Malignant Intracranial Tumours in Adults
    Chapter Outline
    Radiological Investigations in Intracranial Tumours
    Computed Tomography
    Magnetic Resonance Imaging
    Structural MRI
    Advanced Physiological and Molecular Imaging Methods
    MR Spectroscopy
    fMRI
    Classification of Intracranial Tumours
    Intra-Axial Tumours
    Neuroepithelial Tumours
    Gliomas
    The Role of Advanced Physiological MR Imaging in Glial Tumours
    Tumours of Predominantly Neuronal Cell Origin
    Pineal Region Tumours
    Embryonal Neuroepithelial Neoplasms
    Lymphomas
    Metastases
    Intraventricular Tumours
    Ependymoma
    Central Neurocytoma
    Colloid Cyst
    Extra-Axial Tumours
    Meningiomas
    Cranial Nerve Sheath Tumours
    Epidermoid and Dermoid Tumours
    Meningeal Metastases
    Skull Base Tumours
    Chordomas
    Pituitary Region Tumours
    Pituitary Adenomas
    Craniopharyngiomas
    Rathke’s Cleft Cysts
    Further Reading
    Online-only References
    62 Neurovascular Diseases
    Chapter Outline
    Stroke
    Pathophysiology
    The Penumbra Model
    Stroke Classification
    Causes
    Large Vessel Thromboembolic Stroke (40%)
    Borderzone Infarction
    Global Hypoxic–Ischaemic Injury
    Imaging Strategies and Goals in Acute Stroke
    Standard Imaging
    Objectives of NECT in Acute Stroke
    Hyperacute Infarct Imaging Signs
    ASPECTS Infarct Size Scoring System
    Advanced Imaging
    Subacute and Chronic Infarct Imaging Signs
    Atheromatous Extracranial Vascular Disease
    Imaging Options for Carotid Stenosis
    Imaging Signs
    Non-Atheromatous Extracranial Vascular Narrowing
    Arterial Dissection
    Fibromuscular Dysplasia (FMD)
    Intracranial Vascular Disease
    Ischaemic Microangiopathy
    Moya Moya
    Cerebral Venous Thrombosis (CVT)
    Non-Traumatic Intracranial Haemorrhage
    Subarachnoid Haemorrhage (SAH)
    Initial Investigation of Acute SAH
    Aneurysmal SAH
    Angiography in Acute SAH
    Intracerebral Haemorrhage
    Appearance on CT and MRI
    Angiography in Intracerebral Haemorrhage
    Arteriovenous Malformations
    Subdural and Extradural Haemorrhage
    Further Reading
    Online-only References
    63 Intracranial Infections
    Chapter Outline
    Bacterial Infections
    Bacterial Meningitis
    Cerebritis and Brain Abscess
    Epidural Abscess and Subdural Empyema
    Ventriculitis
    Tuberculosis
    Neurosyphilis
    Fungal Infections
    Viral Infections
    Herpes Simplex Encephalitis
    Other Viral Encephalitides
    Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS)
    HIV Encephalopathy
    HIV and Vascular Disease
    Progressive Multifocal Leukoencephalopathy
    ParasItic Infections
    Toxoplasmosis
    Cysticercosis
    Echinococcus (Hydatid Disease)
    Malaria
    Further Reading
    Online-only References
    64 Inflammatory and Metabolic Disease
    Chapter Outline
    Idiopathic Inflammatory-Demyelinating Disorders of the Central Nervous System
    Multiple Sclerosis
    MR Imaging
    Multiple Sclerosis Variants
    Marburg’s Disease
    Tumefactive or Pseudotumoural IIDDs
    Devic’s Neuromyelitis Optica
    Acute Disseminated Encephalomyelitis
    Acute Disseminated Encephalomyelitis Variants
    Primary and Secondary Vasculitis
    Central Nervous System Vasculitis
    Primary Central Nervous System Vasculitis
    Secondary Central Nervous System Vasculitis
    Primary Systemic Vasculitis with Central Nervous System Involvement
    Neurosarcoidosis
    Behçet’s Disease
    Systemic Lupus Erythematosus
    Metabolic and Toxic Disorders in the Adult
    Ethanol Intoxication
    Marchiafava–Bignami Disease
    Wernicke’s Encephalopathy
    Methanol Poisoning
    Diethylene Glycol
    Hepatic Encephalopathy
    Carbon Monoxide
    Heavy Metal Poisoning
    Organic Solvent Poisoning
    Cocaine
    Ecstasy
    Opioids and Derivatives
    Excytotoxic Oedema
    Further Reading
    Online-only References
    65 Neurodegenerative Diseases and Epilepsy
    Chapter Outline
    Ageing and Dementia—Introduction and Clinical
    Normal Ageing Phenomena in the Brain
    Dementia—Imaging Approach
    Indications for Imaging
    Protocol for CT and MRI
    Alzheimer’s Disease and Other Primary Neurodegenerative Dementias
    Alheimer’s Disease
    Frontotemporal Lobar Degeneration
    Vascular Dementia
    Large-Vessel VaD
    Small-Vessel VaD
    CADASIL, Fabry’s Disease and CAA
    Systemic Causes of VaD
    Differential Diagnosis of WM Disorders in Dementia
    Rapidly Progressive and Other Atypical Dementias
    Infectious and Inflammatory Disease
    HIV and PML
    Toxic/Metabolic Disorders
    Parkinson’s Disease and Related Disorders
    Idiopathic Parkinson’s Disease and Differential Diagnosis
    Dementia with Parkinsonism
    Neurodegeneration and Other Movement Disorders
    Epilepsy—Introduction and Clinical
    Classification of Seizures
    Epilepsy—Imaging Approach
    Indications for Imaging
    Imaging Protocol
    Epilepsy—Congenital Disorders
    Migration and Gyration Disorders
    Genetic Syndromes
    Epilepsy—Acquired Diseases
    Hippocampal Sclerosis
    Neoplasms
    Post-Traumatic Epilepsy
    Infections
    Online-only References
    66 Orbit
    Chapter Outline
    The Orbit
    Introduction
    Orbital Anatomy
    Imaging of the Orbit
    Orbital Pathology
    Congenital Disease
    Disorders of Globe Size or Shape
    Orbital Inflammatory Disease
    Benign Neoplasms and Mass-Like Lesions
    Vascular Lesions of the Orbit
    Malignant Neoplasms
    Paediatric Neoplasms
    Ischaemia
    Orbital Trauma
    The Retro-Orbital Visual Pathway
    Introduction
    Anatomy
    Pathologies of the Anterior Visual Pathway (Optic Nerves, Chiasm and Optic Tracts)
    Congenital
    Pathologies of the Posterior Visual Pathway (Lateral Geniculate Nucleus, Optic Radiation and Visual Cortex)
    Other Neuro-Ophthalmological Conditions
    Idiopathic Intracranial Hypertension
    Further Reading
    Online-only References
    67 ENT, Neck and Dental Radiology
    Chapter Outline
    Introduction
    The Ear, Paranasal Sinuses And Nasal Cavity
    The Auricle and External Auditory Canal
    Anatomy
    The Middle Ear
    Anatomy and Physiology
    Pathology
    The Inner Ear
    Anatomy and Physiology
    Pathology
    Cochlear Electrode Implantation
    The Paranasal Sinuses and Nasal Cavity
    Anatomy and Physiology
    Radiology and Pathology
    The Neck
    The Suprahyoid Neck
    Anatomy
    The Infrahyoid Neck
    Anatomy
    Dental and Maxillofacial
    Disorders of Bone
    Developmental Disorders
    Metabolic, Endocrine and Haematological Disorders of Bone
    Tumours of Bone
    Fractures of the Facial Skeleton
    Fractures of the Zygomatic Complex
    Radiological Investigation of Maxillary Fractures
    Fractures of the Mandible
    Temporomandibular Joint Disoders
    Developmental Abnormalities
    Temporomandibular Joint Dysfunction
    Injury
    Salivary Gland Disorders
    Anatomy
    Radiological Techniques and Their Application
    Calculi and Duct Strictures
    Salivary Gland Tumours
    Trauma
    Soft Tissues
    Anatomy of Teeth and Supporting Structures
    Introduction
    Tooth Eruption
    Normal Eruption
    Disorders of Tooth Development
    Disturbances in Structure of Teeth
    Enamel
    Miscellaneous Conditions
    Dental Caries
    Disorders of the Pulp
    Periapical Periodontitis
    Cysts of the Jaws
    Odontogenic Cysts
    Non-Odontogenic Cysts
    Disease of the Periodontium
    Introduction
    Odontomes and Odontogenic Tumours
    Imaging in Implantology
    Trauma
    Teeth
    Further Reading
    Online-only References
    G Oncological Imaging
    68 Principles of Oncological Imaging
    Chapter Outline
    Introduction
    Diagnosis
    Primary Diagnosis
    Confirmation of Diagnosis
    Staging
    Staging Systems
    Principles of Staging Investigations
    Primary Tumour Staging
    Rectal Cancer
    Non-Small Cell Lung Cancer
    Prostate Cancer
    Staging Distant Metastatic Disease
    Assessment of Treatment Response
    The Role of Imaging
    Objective Response Assessment
    Imaging Residual Masses
    Imaging of Treatment Toxicity
    Lung
    Bone and Bone Marrow
    Hepatic Toxicity
    Cardiotoxicity
    Surveillance and Restaging
    Surveillance of Asymptomatic Patients
    Restaging of Symptomatic Patients
    Conclusion
    Further Reading
    Online-only References
    69 The Breast
    Chapter Outline
    Methods of Examination
    Mammography
    Standard Projections
    Additional Projections
    Breast Compression
    Radiation Dose
    Digital Breast Tomosynthesis
    Ultrasound
    Ultrasound Technique
    Normal Anatomy
    Breast Pathology
    Benign Mass Lesions
    Cysts
    Papilloma
    Lipoma
    Invasive Carcinoma
    Classification of Invasive Breast Cancer
    The Differential Diagnosis of Malignancy
    Microcalcifications
    Benign Microcalcifications
    Malignant Microcalcifications
    Additional Imaging Technologies
    Magnetic Resonance Imaging
    Technique
    Indications for Breast MRI
    Controversies Surrounding the Use of Breast MRI
    Nuclear Medicine Techniques
    Breast Cancer Screening
    Introduction
    The Evidence for Screening
    Which Age Groups Should be Screened?
    The Screening Process and Assessment
    Interval Cancers
    How Does Mammographic Screening Reduce Breast Cancer Mortality?
    Quality Assurance (QA)
    Interventional Breast Radiology
    Fine-Needle Aspiration for Cytology and Needle Core Biopsy
    Vacuum-Assisted Biopsy
    Number of Samples
    MRI-Guided Biopsy
    Managing the Result of Needle Biopsy
    Preoperative Localisation of Impalpable Lesions
    Conclusion
    Further Reading
    Online-only References
    70 Reticuloendothelial Disorders:
    Chapter Outline
    Epidemiology
    Age
    Infectious Agents
    Immunosuppression
    Genetic Factors
    Gender and Race
    Histopathological Classification
    Hodgkin’s Lymphoma
    Non-Hodgkin’s Lymphoma
    Staging, Investigation and Management
    Hodgkin’s Lymphoma
    Clinical Features and Staging
    Prognosis and Treatment
    Non-Hodgkin’s Lymphoma
    Clinical Features and Staging
    Lymph Node Disease in Lymphoma
    Imaging Nodal Disease
    Choice of Imaging Technique
    Neck
    Thorax
    Abdomen and Pelvis
    Extranodal Disease in Lymphoma
    Thorax
    Pulmonary Parenchymal Involvement
    Pleural Disease
    Pericardium and Heart
    Chest Wall
    Hepatobiliary System and Spleen
    Liver
    Gastrointestinal Tract
    Stomach
    Colon and Rectum
    Oesophagus
    Genitourinary Tract
    Kidneys
    Bladder
    Adrenal Glands
    Musculoskeletal System
    Bone Marrow
    Central Nervous System
    Primary
    Secondary
    Head and Neck Lymphoma
    Waldeyer’s Ring
    Mucosa-Associated Lymphoid Tissue Lymphomas
    Burkitt’s Lymphoma
    LYMPHOMA in the Immunocompromised
    Lymphomas Associated with HIV
    Post-transplant Lymphoproliferative Disorders
    Monitoring Response to Therapy
    Prognostication
    Response Criteria
    Complete Remission (CR)
    Partial Response (PR)
    Residual Masses
    Computed Tomography
    MRI
    FDG-PET in Response Assessment
    Surveillance and Detection of Relapse
    Conclusion
    Further Reading
    Online-only References
    71 Bone Marrow Disorders:
    Chapter Outline
    Primary Myelofibrosis
    Clinical Features
    Radiological Features
    Systemic Mastocytosis
    Clinical Features
    Radiological Features
    Leukaemia
    Clinical Features
    Radiological Features
    Lymphoma
    Primary Lymphoma of Bone
    Clinical Features
    Radiological Features
    Hodgkin’s Lymphoma
    Clinical Features
    Non-Hodgkin’s Lymphoma
    Clinical Features
    Burkitt’s Lymphoma
    Clinical Features
    Plasma Cell Disorders
    Plasmacytoma
    Clinical Features
    Multiple Myeloma
    Clinical Features
    Further Reading
    Online-only References
    72 Bone Marrow Disorders:
    Chapter Outline
    Disorders of Red Cells
    The Anaemias
    Chronic Haemolytic Anaemias
    The Haemoglobinopathies
    Thalassaemia
    Sickle-Cell Disease
    Miscellaneous Disorders
    Gaucher’s Disease
    Radiological Features
    Disorders of Blood Coagulation
    Haemophilia (Haemophilia A)
    Christmas Disease (Haemophilia B)
    Von Willebrand’s Disease
    Radiological Features
    Further Reading
    Online-only References
    73 Imaging for Radiotherapy Planning
    Chapter Outline
    Types of Radiotherapy
    External Beam Radiotherapy
    Conventional External Beam Radiotherapy
    Three-Dimensional Conformal Radiotherapy
    Intensity-Modulated Radiotherapy (IMRT)
    Stereotactic Body Radiotherapy (SBRT)
    Brachytherapy
    Particle Therapy
    The Radiotherapy Process
    Radiotherapy Treatment Volume Definition
    Clinical Volume Definition (Non-imaging-Based)
    Conventional Simulation
    CT Simulation
    Image Fusion
    Treatment Planning and Verification
    Image Guidance during Radiotherapy Delivery
    Planar (2-Dimensional) Imaging
    Volumetric (3-Dimensional) Imaging
    Four-Dimensional (4D) Imaging
    Functional Imaging in the Radiotherapy Process
    Inclusion of Biological Information to the Treatment Process
    18F-Misonidazole Positron Emission Tomography
    Cu-ATSM Positron Emission Tomography
    Blood Oxygenation Level-Dependent Magnetic Resonance Imaging (BOLD-MRI)
    Further Reading
    Online-only References
    74 Functional and Molecular Imaging for Personalised Medicine in Oncology
    Chapter Outline
    Personalised Medicine in Oncology
    Dynamic Contrast-Enhanced Computed Tomography (DCE-CT)
    Contrast Agent Kinetics
    Magnetic Resonance Imaging (MRI)
    Dynamic Contrast-Enhanced MRI (DCE-MRI)
    Diffusion-Weighted Imaging (DWI)
    MR Spectroscopy (MRS)
    Positron Emission Tomography (PET)
    Fluorodeoxyglucose-PET (FDG-PET)
    Non-FDG-PET Tracers
    Emerging Molecular Imaging Techniques and Theranostics
    Ultrasound
    Optical Imaging
    Conclusion: Role of Functional and Molecular Imaging in Oncology
    Further Reading
    Online-only References
    H Paediatric Imaging
    75 Challenges and Overview of Special Features and Techniques
    Chapter Outline
    Projection Radiography
    Fluoroscopy
    Computed Tomography (CT)
    320-Row MDCT
    Dual-Source CT
    Dual-Energy Dual-Source CT
    Radiation Dose Consideration
    Patient Care
    Dental Cone Beam CT
    Magnetic Resonance Imaging (MRI)
    Patient Preparation
    Radiofrequency Coils
    Motion Artefact Reduction
    Tissue Contrast
    Image Resolution
    Imaging Planes
    Practical Consequences
    Further Reading
    Online-only References
    76 The Neonatal and Paediatric Chest
    Chapter Outline
    The Neonatal Chest
    Normal Anatomy and Artefacts
    Normal Lung Development
    Idiopathic Respiratory Distress Syndrome
    Transient Tachypnoea of the Newborn (TTN)
    Meconium Aspiration Syndrome
    Neonatal Pneumonia
    Air Leaks
    Pleural Effusions
    Surfactant Dysfunction Disorders
    Lines and Tubes
    The Chest in Older Children
    The Chest Radiograph
    Normal Variants
    Cardiac or Respiratory?
    The Lungs
    Pulmonary Infection
    Bacterial vs Viral
    Late Complications of Infection
    The Acutely Wheezing Child
    Congenital Chest Abnormalities
    Malignancy
    Summary
    Further Reading
    Online-only References
    77 Paediatric Abdominal Imaging
    Chapter Outline
    Introduction
    The Neonate
    Visible Abnormalities of the Anterior Abdominal Wall
    Gastroschisis
    Bladder Exstrophy—Epispadias—Cloacal Exstrophy Complex
    Respiratory Distress and Choking
    Oesophageal Atresia and Tracheo-Oesophageal Fistula
    Non-bilious Vomiting
    Obstruction of the Stomach
    Bilious Vomiting
    Small Bowel Malrotation and Volvulus
    Management
    Duodenal Atresia and Stenosis
    Abdominal Distension
    Necrotising Enterocolitis (NEC)
    Colon Atresia
    Megacystis-Microcolon-Intestinal Hypoperistalsis (Berdon’s) Syndrome
    Delayed Passage of Meconium
    Hirschsprung’s Disease
    Functional Immaturity of the Colon and Meconium Plug Syndrome
    Distal Ileal Atresia
    The Infant and Older Child
    Abdominal Pain
    Acute Appendicitis
    Mesenteric Lymphadenitis
    Intussusception
    Constipation
    Intestinal Motility Disorders
    Abdominal Distension
    Enteric Duplication Cysts
    Mesenteric Cysts
    Non-bilious Vomiting
    Gastro-oesophageal Reflux Disease
    Organoaxial Torsion and Gastric Volvulus
    Malrotation with Chronic Intestinal Obstruction or Intermittent Volvulus
    Omphalomesenteric (Vitelline) Duct Remnants
    Meckel’s Diverticulum
    Gastrointestinal Malignancies
    The Immunocompromised Child
    Gastrointestinal Manifestations of Acquired Immune Deficiency Syndrome
    Abdominal Manifestations of Cystic Fibrosis
    Abdominal Trauma
    Liver
    Imaging Techniques
    US
    MRI
    Imaging Anatomy
    Liver Involvement in Congenital Malformation and Infections, Syndromes and Systemic Conditions
    Non-obstructive Jaundice
    Infection
    Chronic Liver Disease
    Cirrhosis
    Non-alcoholic Fatty Liver Disease (NAFLD)
    Portal Vein
    Portosystemic Shunts
    Portal Venous Gas
    Mass Lesions
    Imaging Features
    Mesenchymal Hamartoma (Fig. 77-48)
    Trauma
    Transplant
    Biliary System
    Imaging Techniques
    Imaging Anatomy
    Jaundice
    Biliary Atresia (Fig. 77-50)
    Choledochal Malformation (Choledochal Cyst (Fig. 77-51))
    Persistent Intrahepatic Cholestasis
    Sludge and Gallstones
    Spontaneous Perforation of the Bile Ducts
    Cholangitis
    Sclerosing Cholangitis
    Neoplasia
    Pancreas
    Imaging Techniques
    Imaging Anatomy
    Congenital Abnormalities and Associations
    Pancreas Divisum (Fig. 77-52)
    Annular Pancreas (Fig. 77-53)
    Systemic Disorders
    Cystic Fibrosis
    Pancreatitis
    Trauma
    Congenital Hyperinsulinism
    Neoplasms
    Spleen
    Imaging Techniques
    Imaging Anatomy
    Imaging Findings
    Splenomegaly
    Wandering Spleen
    Lateralisation Disorders (Fig. 77-59)
    Infarction
    Trauma
    Neoplasia
    Further Reading
    Online-only References
    78 Imaging of the Kidneys, Urinary Tract and Pelvis in Children
    Chapter Outline
    Overview
    Imaging Techniques
    Plain Radiography
    Ultrasound
    Standard Technique
    Normal Gonadal Imaging in Girls
    Normal Gonadal Imaging in Boys
    Cystography
    Micturating (Voiding) Cystogram (MCUG/VCUG)
    Contrast-Enhanced Ultrasonography (ce-VUS)
    Nuclear Medicine
    Direct Radio-Isotope Cystogram (DIC)
    Urography (Plain Radiograph and Intravenous Urogram)
    Computed Tomography
    Method
    Magnetic Resonance Imaging
    Method
    Interventional Procedures
    Angiography
    Renal Biopsy
    Congenital Anomalies
    Renal Anomalies
    Renal Agenesis
    Cross Fused Renal Ectopia
    Anomalies of the Renal Pelvis and Ureter
    Megaureter and Hydroureter
    Prune-Belly Syndrome
    Urethral Anomalies
    Posterior Urethral Valves (PUV)
    Uterus and Vagina
    Undescended Testis
    Antenatal Diagnosis of Hydronephrosis
    Prenatal Diagnosis of Renal/Urological Abnormality and Differential Diagnosis
    Unilateral Renal Pelvic Dilatation
    Renal Failure
    Urinary Tract Infection and Vesicoureteric Reflux
    Clinical Setting
    Renal Abscess
    Renal Cystic Disease
    Cystic Dysplasia
    Multicystic Dysplastic Kidney (MCDK)
    Tuberous Sclerosis
    Autosomal Recessive Polycystic Kidney Disease
    Juvenile Nephronophthisis/Medullary Cystic Disease
    Nephrocalcinosis
    Renal Calculi
    Tumours
    Benign Tumours
    Nephroblastomatosis
    Mesoblastic Nephroma
    Malignant Tumours
    Wilms’ Tumour
    Clear Cell Sarcoma of the Kidney
    Lymphoma and Leukaemia
    Inflammatory Diseases of the Scrotum
    Scrotal Masses
    Ovarian Masses
    Ovarian Cysts
    Presacral Masses
    Hypertension
    Trauma
    Renal Transplantation
    Pre-Transplantation
    Further Reading
    Online-only References
    79 Skeletal Radiology in Children:
    Chapter Outline
    Consitutional Disorders of Bone
    Nomenclature
    Prevalence
    Diagnosis
    Prenatal Diagnosis
    Imaging
    Making the Diagnosis
    Assessing Complications
    Management
    Genetic Counselling
    Osteochondrodysplasias
    Chromosomal Disorders
    Trisomy 21 (Down’s Syndrome)
    45XO (Turner’s Syndrome)
    Localised Disorders of the Skeleton
    Sprengel Deformity (Congenital Elevation of the Scapula)
    Madelung Deformity
    Developmental Dysplasia of the Hip
    Femoral Dysplasia (Idiopathic Coxa Vara/Proximal Focal Femoral Deficiency Spectrum)
    Idiopathic Coxa Vara
    Tibia Vara
    Talipes
    Idiopathic Avascular Necrosis of the Femoral Head (Perthes Disease)
    Slipped Capital Femoral Epiphysis (SCFE)
    Scoliosis
    Neurocutaneous Syndromes
    Neurofibromatosis
    Tuberous Sclerosis
    Juvenile Idiopathic Arthritis (JIA)
    Juvenile Dermatomyositis
    Non-Inflammatory Disorders
    Haemophilia
    Pigmented Villonodular Synovitis
    Synovial Osteochondromatosis
    Metabolic and Endocrine Disorders
    Metabolic Disorders
    Rickets
    Vitamin D-Dependent Rickets
    Endocrine Disorders
    Hyperparathyroidism
    Hypothyroidism
    Toxic Disorders
    Fluorosis
    Lead Poisoning
    Haemoglobinopathies
    Sickle Cell Disease
    Thalassaemia
    Infection of the Bones and Joints
    Osteomyelitis
    Chronic Recurrent Multifocal Osteomyelitis
    Infective Arthritis
    Infection of the Spine (Discitis and Osteomyelitis)
    Further Reading
    Online-only References
    80 Paediatric Musculoskeletal Trauma and the Radiology of Non-accidental Injury and Paediatric Factures
    Chapter Outline
    Physeal Injuries
    The Upper Limb
    Shoulder/Humerus
    Elbow
    Forearm/Wrist/Hand
    The Lower Limb
    Pelvis
    Acetabular, Hip and Femur
    Knee
    Tibia/Ankle/Foot
    Tibia
    Ankle
    Foot
    Cervical Spinal Injuries
    Non-accidental injury
    Clinical Presentation and the Role of the Radiologist
    Injury Patterns
    Shaken Baby Syndrome
    General Imaging Strategies
    Skeletal Injury
    The Skeletal Survey
    Bone Scintigraphy
    Fracture Patterns in Accidental vs Non-Accidental Injury
    Rib Fractures
    Metaphyseal Injury
    Long Bone Fractures
    Fracture Healing
    Differential Diagnosis
    Birth Trauma
    Brain Injuries
    Pathophysiology of Skull, Brain and Spinal Canal Lesions
    Imaging in NAHI
    Skull Fractures
    Extra-Axial Haemorrhages
    Parenchymal Brain Injuries
    Diffuse Hypoxic-Ischaemic Lesions
    Intraspinal Lesions
    Strategy and Prognosis
    Abdominal and Chest Injuries
    Imaging
    Online-only References
    81 Bone Tumours and Neuroblastoma in Children
    Chapter Outline
    Bone Tumours
    Malignant Bone Tumours
    Osteosarcoma
    Ewing’s Sarcoma Family of Tumours (ESFTs)
    Rare Malignant Bone Tumours in Children
    Benign Bone Tumours
    Bone-Forming Tumours
    Tumours of Fibrous Tissue Origin
    Cartilage-Forming Tumours
    Vascular and Other Connective Tissue Tumours
    Locally Aggressive Tumours
    Tumour-Like Lesions
    Neuroblastoma
    Imaging
    Radiographs
    Radionuclide Radiology
    NB Staging
    Differential Diagnosis
    Further Reading
    Online-only References
    82 Paediatric Neuroradiology
    Chapter Outline
    Normal Brain Maturation
    Normal Myelination
    Normal Gyral Development
    Other Postnatal Maturational Changes
    Brain Malformations and Developmental Abnormalities
    Posterior Fossa Abnormalites
    Cerebellar Hypoplasia
    Dandy–Walker Malformation and Its Variants
    Joubert’s Syndrome and Related Disorders (JSRD)
    Other Posterior Fossa Malformations or Developmental Disorders
    Chiari II Malformation
    Disorders of Dorsal Induction
    Disorders of Ventral Induction
    Malformations of Commissural and Related Structures
    Malformations of Cortical Development—Histogenesis, Neuronal Migration and Cortical Organisation
    Polymicrogyria
    Schizencephaly
    Grey Matter Heterotopia
    Hemimegalencephaly
    Focal Cortical Dysplasia (FCD)
    Neurocutaneous Syndromes
    Neurofibromatosis Type 1
    Tuberous Sclerosis
    Sturge–Weber Syndrome
    Neurofibromatosis Type 2
    Other Neurocutaneous Syndromes
    Spinal Malformations
    Normal Development
    Definitions
    Open Spinal Dysraphism
    Closed Spinal Dysraphism
    Dorsal Dermal Sinus
    Diastematomyelia
    Neurenteric Cysts
    Disorders of the Caudal Cell Mass/Caudal Regression Syndrome
    Segmental Spinal Dysgenesis
    Inborn Metabolic Brain Disorders
    Craniosynostosis
    Neonatal Nasal Obstruction: Nasal Cavity Stenosis/Atresia
    Choanal Atresia and Pyriform Stenosis
    Skeletal Dysplasias
    Brain Tumours
    The Children’s Cancer and Leukaemia Group (CCLG) Guidelines
    Posterior Fossa Tumours
    Suprasellar Tumours
    Craniopharyngioma
    Hypothalamic–Optic Pathway Glioma
    Infundibular Tumours
    Pituitary Tumours
    Pineal Region Tumours
    Central Nervous System Germ Cell Tumours
    Primary Pineal Tumours: Pineoblastoma and Pineocytoma
    Supratentorial Hemispheric Tumours
    Astrocytomas
    Ependymomas
    Supratentorial Primitive Neuroectodermal Tumours
    Desmoplastic Infantile Gangliomas
    Choroid Plexus Tumours
    Dysembryoplastic Neuroepithelial Tumours
    Cerebrovascular Disease and Stroke
    Hypoxic–Ischaemic Injury in the Developing Brain
    Introduction
    Encephalopathy of Premature Neonate—Patterns of Injury
    Periventricular Leukomalacia
    Brain Haemorrhagic Disease
    Encephalopathy of Term Neonate—Patterns of Injury
    Miscellaneous Acquired Toxic or Metabolic Disease
    Intracranial and Intraspinal Infections
    Congenital Infections (TORCH)
    Meningitis
    Pathophysiology
    Imaging of Complications (Table 82-4)
    Tuberculous Infection
    Bacterial Infection: Cerebritis and Abscess Formation
    Neurocysticercosis
    Viral Encephalitis
    Infection in Immunocompromised Children
    Spinal Infections
    Brain and Cord Inflammation
    Trauma
    Birth Trauma
    Growing Skull Fractures
    Spinal Trauma
    Atlanto-Axial Rotatory Fixation
    Non-Accidental Head Injury
    Hydrocephalus
    Summary
    Further Reading
    Online-only References
    I Interventional Radiology
    83 Basic Clinical Requirements of Interventional Radiology
    Chapter Outline
    IR
    Training
    Clinical Involvement
    Informed Consent
    IR Checklist
    Coagulation
    Contrast Medium Allergy
    Kidney Function
    Sedation and Pain Management
    Benzodiazepines
    Opioids
    Intravenous Anaesthetics
    Complications Register
    The Interventional Radiology Suite
    Inventory
    Online-only References
    84 Angiography:
    Chapter Outline
    Introduction
    Multidetector CT Angiography (MDCTA) Techniques
    Magnetic Resonance Angiography (MRA) Techniques
    Contrast Mechanisms
    Unenhanced Time-of-Flight (TOF) MRA
    New Non-Contrast Techniques
    Clinical Applications of CTA and MRA
    Thorax
    Thoracic Aorta and Great Arteries
    Abdomen
    Abdominal Aorta and Abdominal Veins
    Renal, Mesenteric and Hepatic Arteries
    Carotid and Vertebral Arteries and Intracranial Arteries
    Future Directions
    Catheter Arteriography
    Technique
    Preparation of the Patient
    Contraindications
    Anaesthesia
    Arterial Puncture
    Retrograde Femoral Artery Puncture (Fig. 84-13)
    Antegrade Femoral Artery Puncture
    Selective Catheterisation
    Digital Subtraction Angiography
    Aftercare
    Complications
    Contrast Medium Reactions
    Puncture Site Complications
    Haemorrhage
    Catheter-Related and General Complications
    Further Reading
    Online-only References
    85 Aortic Intervention
    Chapter Outline
    Introduction
    Stent-Grafts and Basic Principles of Stent-Grafting
    Surveillance Imaging and Complications
    Endoleak
    Type 1 Endoleak (Fig. 83-3A)
    Type 3 Endoleak (Fig. 85-3D)
    Device Migration, Dislocation, Kinking and Occlusion
    Infrastructure and Staffing
    Thoracic Aortic Intervention
    Anatomical Considerations
    Thoracic Aortic Aneurysm
    Outcomes of Endovascular Repair and Comparison with Surgery
    Acute Aortic Syndrome
    Thoracic Aortic Dissection
    Management
    Complicated Type B Dissection
    Chronic Dissection and Aneurysmal Development
    Outcomes of Endovascular Repair and Comparison with Surgery
    Acute Intramural Haematoma and Penetrating Ulcer
    Traumatic Lesions of the Thoracic Aorta
    Penetrating Injury to the Thoracic Aorta
    Aortic Coarctation
    Abdominal Aortic Aneurysm
    Anatomical Considerations in AAA repair
    Risks and Timing of Repair
    Outcomes of Endovascular Repair and Comparison with Surgery
    Endovascular Repair of Ruptured AAA
    Thoraco-Abdominal Aneurysms
    Aortic Stenoses and Occlusions
    Summary and Conclusion
    Further Reading
    Online-only References
    86 Peripheral Vascular Disease Intervention
    Chapter Outline
    Interventional Radiology Techniques
    Angioplasty
    Stenting
    Embolisation
    Thrombolysis
    Arterial System
    Pelvic and Lower Extremity Arteries
    Angiographic Anatomy (Fig. 86-5)
    Treatment of Chronic Limb Ischaemia
    Treatment of Acute Lower Limb Ischaemia
    Upper Extremity Arteries
    Anatomy
    Gastrointestinal System
    Angiography (Fig. 86-11)
    Bronchial Artery Embolisation
    The Carotid Arteries
    Imaging
    Venous System
    Lower Extremity Venous System
    Upper Extremity Venous Obstruction
    Inferior Vena Cava Filters
    Complications of Endovascular Procedures
    Further Reading
    Online-only References
    87 Image-Guided Biopsy and Ablation Techniques
    Chapter Outline
    Image-Guided Biopsy
    Introduction
    Principles of Image-Guided Biopsy
    Case Selection
    Pre-Procedural Assessment
    Core Biopsy vs Fine Needle Aspiration
    Biopsy Needles
    Fine Needle Aspiration Cytology Needles
    Sheathed Biopsy Needles
    Coaxial Technique
    Imaging Modalities for Biopsy
    Ultrasound
    CT
    PET CT
    Tips and Tricks
    ‘Look Before you Leap’—Procedural Set Up
    Post-Procedural Care
    Specimen Handling
    Complications and Safety Issues
    Track Seeding
    Conclusion
    Image-Guided Tumour Ablation
    The Case for Tumour Ablation
    The Principles of Tumour Ablation
    Ablative Energies
    Radiofrequency Ablation
    Cryoablation
    Interstitial Laser Photocoagulation
    Image Guidance
    Pre-Procedural Planning
    Peri-Procedural Monitoring
    Understanding and Modifying Tumour Pathophysiology
    Specifics and Current Outcomes
    Renal Cancer
    Summary
    Further reading
    Online-only References
    88 Image-Guided Drainage Techniques
    Chapter Outline
    Indications and Contraindications
    Imaging Guidance
    Patient Preparation and Care
    Catheter Insertion
    Catheter Management
    Specific Drainage Techniques
    Chest
    Hepatic Parenchyma
    Biliary System
    Pancreas and Peripancreatic Region
    Gallbladder
    Urinary Tract
    Spleen
    Subphrenic Collections
    Gastrointestinal Drainage
    Peritoneum
    Deep Pelvic Collections
    Organ Traversal
    Paediatric Patients
    Complications
    Conclusion
    Further Reading
    Online-only References
    89 Hepatobiliary Intervention
    Chapter Outline
    Introduction
    Management of Biliary Obstruction
    Background
    Percutaneous Transhepatic Cholangiography
    Biliary Drainage: External, Internal–External
    Biliary Stenting: Metal, Plastic
    Benign Disease
    Benign Strictures
    Calculous Disease
    Percutaneous Biliary Intervention Complications
    Vascular Interventional Techniques in the Liver
    Chemoembolisation
    Background
    TACE Contraindications
    TACE Literature
    Radioembolisation
    Background
    90Y Administration
    Hepatic Arterial Embolisation for Haemorrhage
    Transjugular Intrahepatic Portosystemic Shunt
    Background
    Imaging
    Complications
    Portal Vein Embolisation
    Background
    Hepatic Venous Interventions: Budd–Chiari Syndrome
    Background
    Treatment
    Further Reading
    Online-only References
    90 Vascular Genitourinary Tract Intervention
    Chapter Outline
    Kidney
    Renal Artery Stenosis
    Background
    Technique for Renal Angioplasty and Stenting
    Renal Denervation (RDN)
    Background
    History of Sympathectomy
    Indications
    Renal Tumours
    Benign
    Renal Arteriovenous Malformation (AVM)
    Renal Artery Aneurysms
    Technique
    Trauma Embolisation
    Kidney
    Ureter
    Bladder
    Prostatic Artery Embolisation
    Fibroid Embolisation
    Uterine Artery Embolisation (UAE)
    Treatment Options
    Imaging
    Safety and Efficacy
    Obstetric Haemorrhage
    Post Partum Haemorrhage
    Causes of PPH
    Technique
    Ectopic Pregnancy and Spontaneous Abortion
    Pelvic Congestion Syndrome
    Treatment
    Varicocoele
    Treatment
    Further Reading
    Online-only References
    91 Non-vascular Genitourinary Tract Intervention
    Chapter Outline
    Introduction
    Percutaneous Renal Access—Important Anatomical Factors
    Renal Position
    Relations of the Kidney
    Pelvicalyceal Anatomy of the Kidney
    Renal Vascular Anatomy
    Other Anatomical Factors Important for Renal Access
    Renal Anatomy and Percutaneous Entry
    General Equipment for Renal Access
    Access Needle
    Guidewires
    Catheters
    Percutaneous Nephrostomy (PCN)
    Techniques
    Patient Preparation and Procedure
    Single Puncture Ultrasound-Guided PCN
    Catheter Fixation and Removal
    Difficult or Complicated Nephrostomy
    Non-dilated Kidneys
    Paediatric Nephrostomy
    Complications of PCN and Management
    Percutaneous Nephrolithotomy (PCNL)
    Technique of PCNL
    Tract Planning
    Tract Dilatation
    Complications of PCNL and Management
    Antegrade Ureteric Stents
    Indications for Ureteric Stents
    Ureteric Stents versus Percutaneous Nephrostomy
    Types of Ureteric Stents
    Plastic Stents
    Practical Aspects of Antegrade Stenting
    Technique of Antegrade Stenting
    Stent Lumen Size
    Further Issues about Ureteric Stents
    Retroperitoneal Looping of Stent/Wire
    False Passage Created during Stricture Cannulation
    Improvement in Stent Position
    Extra-anatomical Stenting
    Monitoring Ureteric Stents
    Exchanging or Removing Stents
    Balloon Dilatation of Ureteric Strictures
    Treatment of Urinary Leaks and Fistulas
    Suprapubic Bladder Catherisation
    Managing a Non-Deflatable Urinary Catheter Balloon
    Percutaneous Cystolithotripsy (PCCL)
    Interventional Procedures in the Prostate Gland and Seminal Vesicles
    Drainage of Prostate and Perirectal Abscess
    Seminal Vesiculography and Cyst Sampling
    Prostate Brachytherapy, Cryotherapy and HIFU Prostate Ablation
    Ablation of Renal Cysts or Lymphoceles
    Further Reading
    Online-only References
    92 Venous Access and Interventions
    Chapter Outline
    General Assessment of Patients before Vascular Access Procedures
    General Patient and Interventional Suite Preparation for Central Venous Access
    Insertion of Tunnelled Central Venous Catheter
    Hickman Line
    Groshong Catheter
    Port-a-Cath Placement
    Peripherally Inserted Central Catheters
    Catheter Maintenance
    Catheter Repositioning
    Tunnelled Dialysis Catheters
    Dialysis Catheter Maintenance
    Further Reading
    Online-only References
    93 Spinal Interventions
    Chapter Outline
    Introduction
    Image-Guided Vertebral Biopsy
    Patient Preparation
    Image Guidance
    Performing the Procedure
    Results
    Spinal Injection Procedures
    Lumbar Disc Herniation
    Indications
    Complications
    Pulsed Radiofrequency Ablation
    Facet Joint Syndrome
    Technique
    Cervical Spine
    Percutaneous Disc Decompression
    Technique
    Percutaneous Vertebral Augmentation
    Ablation of Spinal Tumours
    Complications
    Osteoid Osteomas
    Embolisation of Spinal Tumours
    Further Reading
    Subject Index
    A
    B
    C
    D
    E
    F
    G
    H
    I
    J
    K
    L
    M
    N
    O
    P
    Q
    R
    S
    T
    U
    V
    W
    X
    Y
    Z


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    Grainger & Allison's Diagnostic Radiolog
    📂 Library 📅 2014 🏛 Churchill Livingstone 🌐 English

    <p><span>Long recognized as the standard general reference in the field, this completely revised edition of  Grainger and Allison?s Diagnostic Radiology provides all the information that a trainee needs to master to successfully take their professional certification examinations as well as providing

    Grainger & Allison's Diagnostic Radiolog
    ✍ Adam, Andreas Ed 📂 Library 📅 2014 🏛 Churchill Livingstone 🌐 English

    Long recognized as the standard general reference in the field, this completely revised edition of Grainger and Allison's Diagnostic Radiology provides all the information that a trainee needs to master to successfully take their professional certification examinations as well as providing the pract