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GR138676, a novel peptidic tachykinin antagonist which is potent at NK3 receptors

✍ Scribed by J.M. Stables; I.J.M. Beresford; S. Arkinstall; S.J. Ireland; D.M. Walsh; P.W. Seale; P. Ward; R.M. Hagan

Book ID
113237311
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
819 KB
Volume
27
Category
Article
ISSN
0143-4179

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πŸ“œ SIMILAR VOLUMES

The development of a novel series of non
The development of a novel series of non-peptide tachykinin NK3 receptor selective antagonists
✍ P. Boden; J.M. Eden; J. Hodgson; D.C. Horwell; M.C. Pritchard; J. Raphy; N. Suma πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 222 KB

In this paper we describe the transformation of a series of modified dipeptide NK 3 receptor selective ligands, previously developed from a hit identified from the screening of a dipeptide chemical library, into non-peptide, nanomolar affinity NK 3 receptor selective antagonists eg. PD160946 and PD1