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G.P.4.13 A co-inducer of the heat shock response ameliorates disease in a mouse model of SBMA

โœ Scribed by N. Nirmalananthan; J.R.T. Dick; A.R. La Spada; L. Greensmith; M.G. Hanna


Book ID
116793555
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
45 KB
Volume
18
Category
Article
ISSN
0960-8966

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โœ Hua Zhang; Alice Y.-C. Liu ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 723 KB

Submicromolar concentrations of tributyltin (TBT), a commercially used organotin compound, were found to induce the expression of several stress proteins, most notably HSP89 and HSP70, in IMK-90 human diploid fibroblasts in a time-and dose-dependent manner. This induction can be demowtrated by quant