BRCA1 and BRCA2 mutations in women with
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Lenka Foretova; Eva Machackova; Marie Navratilova; Hana Pavlu; Marcela Hruba; Mi
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Article
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2004
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John Wiley and Sons
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English
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Germline mutations in BRCA1 and BRCA2 account for majority of hereditary breast and ovarian cancer. The complete coding sequence analysis of both genes was carried out in 197 breast/ovarian cancer patients from high-risk families and 53 patients with sporadic breast/ovarian cancer. In summary, 59 mu