Gold(I)-Catalyzed Reactions of Propargyl Esters with Vinyl Derivatives

✍ Scribed by Christian A. Sperger; Jørn E. Tungen; Anne Fiksdahl

• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 277 KB
• Volume: 2011
• Category: Article
• ISSN: 1434-193X
• DOI: 10.1002/ejoc.201100291

✦ Synopsis

Abstract

A gold‐catalyzed olefin cyclopropanation reaction of propargyl esters with vinyl ester or vinyl sulfonamide derivatives was investigated for the synthesis of highly substituted cyclopropane derivatives in good diastereoselectivity. By varying the vinyl species, trans‐cyclopentenyl esters were selectively formed by a formal [3+2] cycloaddition.