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Gold-Catalyzed Redox Synthesis of Imidazo[1,2- a ]pyridines using Pyridine N -Oxide and Alkynes

✍ Scribed by Talbot, Eric P. A.; Richardson, Melodie; McKenna, Jeffrey M.; Toste, F. Dean


Book ID
124057311
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
374 KB
Volume
356
Category
Article
ISSN
1615-4150

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Solid-phase synthesis of imidazo[1,2-a]p
✍ Saı̈d El Kazzouli; Sabine Berteina-Raboin; Abderrahim Mouaddib; GΓ©rald Guillaume πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 409 KB

The synthesis of imidazo [1,2-a]pyridine and imidazo[1,2-a]pyrimidine derivatives by condensation between an a-bromoketone bound to solid support and various 2-aminopyridine or 2-aminopyrimidine derivatives was described. Either an acid labile linker or a base labile linker was used in this study.