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Gold-catalyzed Alkyne Hydroxylation: Synthesis of 2-Substituted Benzo[b]furan Compounds

✍ Scribed by Yuan ZHANG; Zhi-Jun XIN; Ji-Jun XUE; Ying LI


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
78 KB
Volume
26
Category
Article
ISSN
0256-7660

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Controlled Synthesis of 2-and 3-Substituted Benzo[b]furans. -Depending on the conditions, C2-substituted benzofuran (IV) or C3-substituted isomer (V) is formed via the same intermediate (III). At temperatures above -30Β°C, 2-substituted benzofurans (VII) and (XI) are generated by intramolecular conde