There is increasing evidence that genetic factors may play some role in the pathogenesis of systemic lupus erythematosus (SLE). The observations that support this hypothesis include: an increased concordancy of SLE in identical twins (1); an increased frequency of SLE and autoimmune phenomena in rel
Gm(1) and Gm(2) immunglobulin allotypes in patients with malignant melanoma
โ Scribed by W. Schultheis; H. H. Peter; H. Deicher
- Book ID
- 104700474
- Publisher
- Springer
- Year
- 1975
- Tongue
- English
- Weight
- 301 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
โฆ Synopsis
Gm allotype markers were determined in sera from 71 melanoma patients and 400 control persons. There was no significant difference between both groups in Gm distribution. The results were compared to a recent report. Furthermore, in 25 malanoma patients the capacity of serum to interfere with cell-mediated cytotoxicity (CMC) of autologous lymphocytes was determined and related to the Gm allotype.
๐ SIMILAR VOLUMES
Fifteen polymorphic systems of the blood (ABO, MNSs, Rhesus, P, Kell, Duffy, Kidd, Hp, Gc, Gm, Inv, aP, PGM1, EsD, and 6-PGD) were examined in 191 unrelated male and female patients suffering from malignant melanoma. These polymorphic systems were compared with the corresponding phenotype and gene f