Thermolysis of the glycosylidene-derived 0 -benzylated diazirine 1 in the presence of N-phenylmaleimide (2), acrylonitrile (3), dimethyl fumarate (4), or dimethyl maleate (5) led in good yields to mixtures of the spirocyclopropanes 6/7, S l l , 12/13, and 12/13/16/17. The diastereoselectivity depend
Glycosylidene Carbenes Part 12. A new synthesis and some reactions of spirooxiranes
โ Scribed by Andrea Vasella; Preeti Dhar; Christian Witzig
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- German
- Weight
- 750 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0018-019X
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โฆ Synopsis
We found no indication for the intermediate formation of diazo compounds (cf. [14]).
๐ SIMILAR VOLUMES
A new approach towards the synthesis of glycosides based upon a (formal) insertion of glycosylidene carbenes into 0-H bonds is presented. The synthesis and characterization of the glycosylidene-derived diazirines 25-28, precursors of glycosylidene carbenes, are described. The diazirines were prepare
After chromatography. b, Determined from the 'H-NMR spectrum of the crude product. ') In C6D, at 300 K (the nuclei involved are 'H, I3C, and Il9Sn). b, Averaged values of the "'Sn and "'Sn coupling constants. ") With TMS as standard. d, With SnMe, as standard.
Synthesis and Reactions of Some New Benzimidazoles. Part 2. -Starting from known, biologically active compounds of type (III) various modifications are carried out to test new types of compounds for their antimicrobial activity. Compounds (VI), (VIIIa), and (XI) show moderate activity against Pseud