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Glycosylation under Thermodynamic Control: Synthesis of the Di- and the Hexasaccharide Fragments of the O-SP of Vibrio Cholerae O:1 Serotype Ogawa from Fully Functionalized Building Blocks

✍ Scribed by Roberto Adamo; Pavol Kováč


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
270 KB
Volume
2007
Category
Article
ISSN
1434-193X

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Methyl 4-(3-deoxy-L-glycero-tetronamido)-4,6-dideoxy-2-O-methyl-alpha-D- mannopyranoside was acetylated, and the fully protected methyl glycoside was treated with dichloromethyl methyl ether-ZnCl2 (DCMME-ZnCl2) reagent to give 3-O-acetyl-4-(2,4-di-O-acetyl-3- deoxy-L-glycero-tetronamido)-4,6-dideoxy