𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Glycosylation of type II collagen is of major importance for T cell tolerance and pathology in collagen-induced arthritis

✍ Scribed by Johan Bäcklund; Alexandra Treschow; Robert Bockermann; Björn Holm; Lotta Holm; Shohreh Issazadeh-Navikas; Jan Kihlberg; Rikard Holmdahl


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
174 KB
Volume
32
Category
Article
ISSN
0014-2980

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Breaking T cell tolerance against self t
✍ Tsvetelina Batsalova; Balik Dzhambazov; Patrick Merky; Alexandra Bäcklund; Johan 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 142 KB

## Abstract ## Objective To establish a new animal model in DRB1\*0401 (DR4)–transgenic mice in which T cell tolerance to self type II collagen (CII) can be broken and allow for the development of autoimmune arthritis, to investigate the role of posttranslational modifications of the CII^259–273^

The impact of glycosylation on HLA–DR1–r
✍ Alexei von Delwig; Daniel M. Altmann; John D. Isaacs; Clifford V. Harding; Rikar 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 254 KB

## Abstract ## Objective Type II collagen (CII) is a candidate autoantigen implicated in the pathogenesis of rheumatoid arthritis (RA). Posttranslational glycosylation of CII could alter intracellular antigen processing, leading to the development of autoimmune T cell responses. To address this po