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Epitope glycosylation plays a critical role for T cell recognition of type II collagen in collagen-induced arthritis

✍ Scribed by Alexandre Corthay; Johan Bäcklund; Johan Broddefalk; Erik Michaëlsson; Tom J. Goldschmidt; Jan Kihlberg; Rikard Holmdahl


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
222 KB
Volume
28
Category
Article
ISSN
0014-2980

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The impact of glycosylation on HLA–DR1–r
✍ Alexei von Delwig; Daniel M. Altmann; John D. Isaacs; Clifford V. Harding; Rikar 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 254 KB

## Abstract ## Objective Type II collagen (CII) is a candidate autoantigen implicated in the pathogenesis of rheumatoid arthritis (RA). Posttranslational glycosylation of CII could alter intracellular antigen processing, leading to the development of autoimmune T cell responses. To address this po