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Glycosylation Assists Binding of HIV Protein gp120 to Human CD4 Receptor

✍ Scribed by Dr. Dennis Wilhelm; Dipl.-Chem. Henning N. Behnken; Prof. Dr. Bernd Meyer


Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
619 KB
Volume
13
Category
Article
ISSN
1439-4227

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The mechanisms accounting for T cell depletion in AIDS patients are not yet fully understood, nor are the roles of host factors in HIV pathogenesis. We show here that an ongoing humoral immune response to HIV gp120 can sensitize non-infected cells towards apoptosis. Thus, i.v. injection of 1 ? g rec