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Glycogen synthase kinase-3β is a crucial mediator of signal-induced RelB degradation

✍ Scribed by Hollenbach, E; Kavuri, S; Leverkus, M; Kandolf, R; Brunner-Weinzierl, M C; Klingel, K; Neumann, M; Klar, S; Wilisch-Neumann, A

Book ID: 109972696
Publisher: Nature Publishing Group
Year: 2011
Tongue: English
Weight: 538 KB
Volume: 30
Category: Article
ISSN: 0950-9232
DOI: 10.1038/onc.2010.580

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## Abstract Excitotoxicity and cell death induced by glutamate are involved in many neurodegenerative disorders. We have previously demonstrated that excitotoxicity induced by millimolar concentrations of glutamate in hippocampal slices involves apoptotic features and glutamate‐induced glutamate re