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Glycogen synthase kinase-3β (GSK-3β) and its dysregulation in glioblastoma multiforme

✍ Scribed by Atkins, R.J.; Stylli, S.S.; Luwor, R.B.; Kaye, A.H.; Hovens, C.M.


Book ID
122497079
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
807 KB
Volume
20
Category
Article
ISSN
0967-5868

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## Glycogen synthase kinase-3␤ (GSK-3␤ ) is a multifunctional protein kinase that phosphorylates a variety of substrates including the neuronal-specific microtubuleassociated protein tau. Here we report that the downregulation of the GSK-3␤ protein is an early event in the course of the differenti