Glycine-amide effect on the vasopressin stimulated sodium and water transport across toad bladder
β Scribed by Wright, D.W.; Snart, R.S.
- Book ID
- 123530729
- Publisher
- Elsevier Science
- Year
- 1971
- Tongue
- English
- Weight
- 405 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0300-9629
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## Abstract Because melatonin mimics the effects of microtubular disruptive agents (e.g., colchicine) in various cellular systems, we have examined its effect on water transport in the toad urinary bladder. Microtubules are essential to vasopressinβstimulated water transport in this tissue and are
Vasopressin increases the permeability of receptor cells t o water and, in tissues such as toad bladder, t o solutes such as urea. While cyclic AMP appears t o play a major role in mediating the effects of vasopressin, there is evidence that activation of the water permeability system and the urea p