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Glycation of human serum albumin by acylglucuronides of nonsteroidal anti-inflammatory drugs of the series of phenylpropionates

✍ Scribed by Hélène Georges; Isabelle Jarecki; Patrick Netter; Jacques Magdalou; Françoise Lapicque


Book ID
117176423
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
556 KB
Volume
65
Category
Article
ISSN
0024-3205

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The binding of representative chemical classes of nonsteroidal anti-inflammatory drugs (NSAIDs) to human serum albumin (HSA) was investigated by equilibrium dialysis. Warfarin enantiomers were used as specific markers in displacement studies. Data were analyzed by a computerized nonlinear least squa