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Association of Valdecoxib, a Nonsteroidal Anti-Inflammatory Drug, with Human Serum Albumin

✍ Scribed by Encinas, Maria V.; Lissi, Eduardo; Vergara, Claudio

Book ID
124068062
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
326 KB
Volume
89
Category
Article
ISSN
0031-8655

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Structural requirements for binding of nonsteroidal anti-inflammatory drugs to human serum albumin
✍ Kim L. Li; Ajit K. Thakur; Amrit L. Kapoor πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 541 KB

The binding of representative chemical classes of nonsteroidal anti-inflammatory drugs (NSAIDs) to human serum albumin (HSA) was investigated by equilibrium dialysis. Warfarin enantiomers were used as specific markers in displacement studies. Data were analyzed by a computerized nonlinear least squa