𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Glutathione redox cycle dysregulation in Huntington’s disease knock-in striatal cells

✍ Scribed by Márcio Ribeiro; Tatiana R. Rosenstock; Teresa Cunha-Oliveira; Ildete L. Ferreira; Catarina R. Oliveira; A. Cristina Rego


Book ID
118447300
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
909 KB
Volume
53
Category
Article
ISSN
0891-5849

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Striatal specificity of gene expression
✍ Elizabeth A. Thomas 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 360 KB 👁 1 views

## Abstract Huntington's disease (HD) is a progressive neurodegenerative disorder caused by an expanded CAG repeat region in exon 1 of the HD gene. This mutation results in the presence of an abnormally long polyglutamine tract in the encoded protein, huntingtin (htt). A major question in this fiel

Ubiquitin-proteasome system alterations
✍ Jesse M. Hunter; Mathieu Lesort; Gail V.W. Johnson 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 505 KB

## Abstract Huntington's disease (HD) is a progressive, autosomal dominant neurodegenerative disease caused by an abnormally expanded CAG repeat in the HD gene. Ubiquitylated aggregates containing mutant huntingtin protein in neurons are hallmarks of HD. Misfolded mutant huntingtin monomers, oligom