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Isolation of circulating metabolites in drug discovery using high-performance liquid chromatography, and their identification by liquid chromatography coupled with tandem mass spectrometry and nuclear magnetic resonance spectroscopy

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Isolation of circulating metabolites in drug discovery using high-performance liquid chromatography, and their identification by liquid chromatography coupled with tandem mass spectrometry and nuclear magnetic resonance spectroscopy One of the major components of modern drug discovery is the structu

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✍ Skogerson, Kirsten; Runnebaum, Ron; Wohlgemuth, Gert; de Ropp, Jeffrey; Heymann, 📂 Article 📅 2009 🏛 American Chemical Society 🌐 English ⚖ 925 KB

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Biotransformation of 12 C- and 2- 13 C-Labeled Methyl tert -Butyl Ether, Ethyl tert -Butyl Ether, and tert -Butyl Alcohol in Rats: Identification of Metabolites in Urine by 13 C Nuclear Magnetic Resonance and Gas Chromatography/Mass Spectrometry

✍ Bernauer, Ulrike; Amberg, Alexander; Scheutzow, Dieter; Dekant, Wolfgang 📂 Article 📅 1998 🏛 American Chemical Society 🌐 English ⚖ 129 KB