𝔖 Bobbio Scriptorium
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GLUCURONIDATION OF DIHYDROCODEINE BY HUMAN LIVER MICROSOMES AND THE EFFECT OF INHIBITORS

✍ Scribed by Lynette C Kirkwood; Roger L Nation; Andrew A Somogyi*

Book ID
108937231
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
177 KB
Volume
25
Category
Article
ISSN
0305-1870

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Glucuronidation of olanzapine by cDNA-ex
Glucuronidation of olanzapine by cDNA-expressed human UDP-glucuronosyltransferases and human liver microsomes
✍ Kristian Linnet πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 72 KB

Olanzapine is a widely used, newer antipsychotic agent, which is metabolized by various pathways: hydroxylation and N-demethylation by cytochrome P450, N-oxidation by flavin monooxygenase and direct glucuronidation. In vivo studies have pointed towards the latter pathway as being of major importance