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Glucuronidation of apomorphine

✍ Scribed by R.S. El-Bachá; S. Leclerc; P. Netter; J. Magdalou; A. Minn


Book ID
117172516
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
192 KB
Volume
67
Category
Article
ISSN
0024-3205

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Convenient synthesis of (S)-(+)-apomorph
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A method was devised for preparing (S)-(+)-apomorphine from (R)-(-)-apomorphine. Dehydrogenation of the dimethyl ether of (R)-(-)-apomorphine with 10% palladium-on-carbon followed by reduction with sodium cyanoborohydride under acidic conditions resulted in quantitative racemization to give (R,S)-ap

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